96129-85-0

Upstream product

• 50-00-0 formaldehyd 
• 781-35-1 1,1-diphenylacetone 
• 593-51-1 methylamine hydrochloride 

Downstream Products

• 96129-98-5 3',4',5',6',7',8'-hexahydro-1,6'-dimethyl-5,5,8,8'-tetraphenylspiropyrano<3,2-c>pyridin>-4-one 
• 96129-96-3 1-methyl-3,3-diphenyl-5-(phenylmethylene)-4-piperidinone 
• 96129-97-4 5-<(3,4-dimethoxyphenyl)methylene>-1-methyl-3,3-diphenyl-4-piperidinone 
• 96129-94-1 1-methyl-3,3-diphenylpiperidin-4-yl ester hydrochloride 
• 96130-00-6 3',4',5',6',7',8'-hexahydro-1,6'-dimethyl-5,5,8,8'-tetraphenylspiropyrano<3,2-c>pyridin>-4-ol 
• 96130-01-7 decahydro-2,8-dimethyl-4,4,6,6-tetraphenyl-4a,9a-epoxy-2H,7H-oxepino<3,2-c:6,7-c'>dipyridine 
• 96129-92-9 1-methyl-3,3-diphenyl-4-piperidinol 
• 96129-95-2 1-Methyl-5,5-diphenyl-piperidine-3,4-dione 3-oxime 

Relevant academic research and scientific papers

The Mannich Reaction. 1-Alkyl-3,3-diphenyl-4-piperidinones, 1,6'-Dialkyl-3',4',5',6',7',8'-hexahydro-5,5,8',8'-tetraphenylspiropyranopyridin>-4-ones and Their Derivatives

Condensation of 1,1-diphenyl-2-propanone with methyl- and ethylamine hydrochloride and a large excess of paraformaldehyde in refluxing methanol gave 1-alkyl-3,3-diphenyl-4-piperidinones (1) as the main isolable products.When the reaction was carried out at 120 deg C, there resulted dimeric compounds 1,6'-dialkyl-3',4',5',6',7',8'-hexahydro-5,5,8',8'-tetraphenylspiropyranopyridin>-4-ones (4) as the major products.Reduction of the dimer 4a (alkyl = methyl) gave 3',4',5',6',7',8'-hexahydro-1,6'-dimethyl-5,5,8',8'-tetraphenylspiropyranopyridin>-4-ol (10) which, on treatment with hot hydrobromic acid, was transformed into the tetracyclic ketal decahydro-2,8-dimethyl-4,4,6,6-tetraphenyl-4a,9a-epoxy-2H,7H-oxepinodipyridine (11).