96133-99-2Relevant academic research and scientific papers
Sulfamic acid-mediated, efficient, one-pot synthesis of novel 5-substituted 1,3,4-thiadiazol-2-ylcarbamoyl aliphatic amide acid derivatives and facile synthesis of cyclic amides
Toche,Janrao,Gangurde,Nikam
supporting information, p. 2527 - 2535 (2013/07/25)
Convenient and efficient one-pot syntheses of 5-substituted-1,3,4- thiadiazol-2- ylcarbamoyl aliphatic amide acid derivatives were described and developed using sulfamic acid catalyst. Thiosemicarbazide and substituted triethylorthoester and cyclic/alicyc
Derives de la dihydro-2,4 triazole-1,2,4 thione-3 et de l'amino-2 thiadiazole-1,3,4 a partir de nouvelles thiosemicarbazones d'esters
Malbec, Frederique,Milcent, Rene,Barbier, Geo
, p. 1689 - 1698 (2007/10/02)
A new general synthesis of 4,5-disubstituted 2,4-dihydro-1,2,3-triazole-3-thiones is proposed.These heterocycles are obtained by the action of primary amines, aralhydrazines or aroylhydrazines on the thiosemicarbazones of esters.These last compounds are prepared by action of chlorhydrates of iminoesters on thiosemicarbazide in dimethylformamide.These thiosemicarbazones react also with strong acids, acid anhydrides and chlorides; by thermolysis and they give 2-amino-1,3,4-thiadiazole derivatives.Also, two derivatives of 1,2,4-triazolo-1,3,4-thiadiazole have been prepared.
