96159-85-2

Usage

Structure

A five-membered thiazole ring with a bromine atom attached to a phenyl ring at the 3-position (the compound contains a heterocyclic ring with both sulfur and nitrogen atoms, and a bromine atom is attached to the phenyl ring)

Potential applications

Pharmaceutical, agrochemical, and material science industries (the compound may have potential uses in these fields)

Building block for synthesis

The compound may serve as a building block for the synthesis of new organic compounds with interesting properties (it can be used to create new compounds with unique characteristics)

InChI:InChI=1/C9H8BrNS/c10-8-3-1-2-7(6-8)9-11-4-5-12-9/h1-3,6H,4-5H2

Upstream product

• 6952-59-6 3-cyanobromobenzene 
• 156-57-0 2-mercaptoethylamine hydrochloride 
• 60-23-1 Cysteamine 

Downstream Products

• 96160-05-3 2-(3-Bromo-phenyl)-3-methyl-4,5-dihydro-thiazol-3-ium; iodide 

Relevant academic research and scientific papers

A straightforward metal-free synthesis of 2-substituted thiazolines in air

A base-catalysed procedure for the synthesis of 2-substituted thiazolines from nitriles and cysteamine hydrochloride under solvent-free conditions is presented. This straightforward approach allows high conversion for a broad range of nitriles and an easy

1,3-Dibromo-5,5-dimethylhydantoin as an efficient homogeneous catalyst for the synthesis of 2-arylthiazolines and 2-arylimidazolines

A simple, facile, and efficient procedure for the synthesis of 2-arylthizolines and 2-arylimidazolines has been developed by the simple condensation of nitriles with 2-aminoethanethiol or ethylenediamine catalyzed by 1,3-dibromo-5,5-dimethylhydantoin under solvent-free conditions. Selective preparation of bisthiozolines and monoimidazolines from dinitriles and also selective conversion of arylnitriles to their corresponding 2-arylthiazolines or imidazolines in the presence of alkylnitriles can be considered as considerable advantages of this method.

Research on radioprotective agents: Δ-2 Thiazolines and homologous derivatives

Compounds derived from Δ-2 thiazoline, Δ-2 thiazolinium iodoalkylate and 4,5-dihydro-1,3 thiazine have been prepared and evaluated as potential antiradiation agents in mice. They generally have a low toxicity and significant radioprotective activity.