96201-07-9Relevant academic research and scientific papers
The Precursor Scan. A New Type of Experiment in Neutralization-Reionization Mass Spectrometry
Gu, Ming,Turecek, Frantisek
, p. 1135 - 1143 (1993)
A new scan technique utilizing the tandem quadrupole acceleration-deceleration mass spectrometer is described.The technique is based on combined monitoring of neutral and ion precursors that fragment following collisional electron transfer to give rise to a selected low-mass neutral species and its ion, respectively.PO(.) is found to be a stable neutral species formed by dissociations of a variety of oxidized phosphorus compounds, such as di- and trialkyl phosphites, phosphates and phosphonic esters.These compounds can be selectively monitored through PO(.) precursor scans in multi-component mixtures.Interferences from isobaric neutral species, 35ClC(.), CH3S(.), CH330SiH2(.), and their precursors are discussed.Neutralization-reionization spectra of phosphorus-containing radicals, PO(.), CH3OPH(.), CH3OPOH(.), (.)P(OCH3)2 and (CH3O)2PO(.), are also reported.
Solid-phase synthesis for novel nerve agent adducted nonapeptides as biomarkers
Li, Xinhai,Yuan, Ling,Wang, Qinggang,Liang, Longhui,Huang, Guilan,Li, Xiaosen,Zhang, Chunhong,Liu, Shilei,Liu, Jingquan
, p. 1437 - 1440 (2017/03/23)
An efficient synthesis of d5-VX adducted nonapeptide and d15-GD adducted nonapeptide via solid-phase approach has been developed. The deuterated peptides could be used as the isotope-labeled internal standard for LC-MS/MS detecting the BuChE-OPNA biomarkers. This method also offers an access to the synthesis and detection of other phosphorylated nonapeptides.
A stable isotope deuterium-labeled organophosphorus insecticide method for the synthesis of
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Paragraph 0069; 0071; 0072, (2016/10/09)
The invention relates to a synthesis method of a stable isotope deuterium-labeled organophosphorus insecticide. The synthesis method comprises the steps of: making stable isotope deuterium-labeled or natural abundance methyl alcohol react with phosphorus trichloride to generate a stable isotope deuterium-labeled dimethyl phosphite or trimethyl phosphite, and then making the stable isotope deuterium-labeled dimethyl phosphite or trimethyl phosphite react with stable isotope deuterium-labeled or natural abundance trichloracetic aldehyde to obtain the stable isotope deuterium-labeled organophosphorus insecticide. Compared with the prior art, the stable isotope deuterium-labeled trichlorphon or dichlorvos provided by the invention has the advantages that the chemical purity reaches above 98.0 percent and the isotope abundance reaches above 98.0 percent atomD after being separated and purified, thus fully meeting the demand on residue detection in the field of food safety.
Molecular mechanisms of additive fortification in model epoxy resins: A solid state NMR study
Kins, Christoph F.,Dudenko, Dmytro,Sebastiani, Daniel,Brunklaus, Gunther
experimental part, p. 7200 - 7211 (2011/10/19)
The bulk properties of polymers are often adjusted via addition of a complex blend of compounds collectively known as additives, where so-called molecular fortifiers (or antiplasticizers) may improve the mechanical properties. In the present work, insight into molecular mechanisms of additive-fortification in model epoxy resins was obtained from multinuclear solid-state NMR analysis. In particular, we have demonstrated a "free molecule"-type behavior of DMSO-d6 in DMSO-fortified resins similar to common inclusion compounds thereby revealing mere filling of free volume. In case of DMMP-fortified resins, however, chemical modification during postcure of the epoxy resin is observed yielding methyl methylphosphonate (MMP) and salt formation, where dynamic heterogeneities of MMP-d3 suggest a rather complex mechanism of fortification. The interpretation of NMR data was further supported by ab initio calculations.
GC-MS STUDY OF THE IMIDE - AMIDE REARRANGEMENT
Gilyarov, V. A.,Shcherbina, T. M.,Laretina, A. P.,Kabachnik, M. I.
, p. 1931 - 1934 (2007/10/02)
The imide - amide rearrangement of trialkyl arylimidophosphates by the action of catalytic amounts of boron trifluoride etherate proceeds at least partially by an intermolecular mechanism.Keywords: capillary gas-liquid chromatography/mass spectrometry, im
Vibrational spectra and possible conformers of dimethylmethylphosphonate by normal mode analysis
Moravie, R. M.,Froment, F.,Corset, J.
, p. 1015 - 1024 (2007/10/02)
A careful assignment of the i.r. and Raman spectra of CH3P(O)(OCH3)2, CD3P(O)(OCH3)2, CH3P(O)(OCD3)2 and CD3P(O)(OCD3)2 and a comparison with those of the parent molecules CH3OP(O)Cl2 and CD3OP(O)Cl2 suggest that only one conformer exists in the liquid state.This conformer is probably close to the most stable one calculated by CNDO/2 and ab initio STO-3G methods, with one CH3O group trans and the other cis to the P=O group.The characteristic modes of the CP(O)(OC)2 skeleton are analysed through a force field calculation.It is shown that the stretching vibrations of the single bonds PC and PO are strongly coupled.As already observed for carboxylic esters, it is shown that only mixed skeletal modes and mostly the bending modes are sensitive to the conformation of the methoxy groups around the P-O single bond.On the other hand the ν(P=O) mode does not vary for the different conformers, and the extra components appearing in its vicinity, as well as in that of the ν(P-C) main vibrational mode, are best understood as being due to Fermi resonances with harmonic or combination tones coupling with these modes.
