96251-59-1

Usage

InChI:InChI=1/C19H23N3O4/c1-21-12-7-11(19(24)25)18(21)13-6-10-4-3-5-16(26-2)17(10)15(9-23)22(13)14(12)8-20/h3-5,11-15,18,23H,6-7,9H2,1-2H3,(H,24,25)

Upstream product

• 143-33-9 sodium cyanide 
• 84573-33-1 (-)-quinocarcin 
• 115288-95-4 C₂₀H₂₇N₃O₄ 
• 115288-96-5 C₂₁H₂₉N₃O₄ 
• 115288-69-2 3-[Dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-benzaldehyde 
• 100-83-4 meta-hydroxybenzaldehyde 
• 115288-97-6 C₂₁H₂₇N₃O₅ 
• 139527-61-0 (2-{(R)-1-[(1R,5S,6R)-6-((1R,5S,7S)-10,10-Dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]decane-4-carbonyl)-8-methyl-2,4-dioxo-3,8-diaza-bicyclo[3.2.1]oct-3-yl]-2-methoxymethoxy-ethyl}-3-methoxy-benzyl)-triphenyl-phosphonium; bromide 
• 139527-60-9 (1R,5S,6R)-3-[(R)-1-(2-Bromomethyl-6-methoxy-phenyl)-2-methoxymethoxy-ethyl]-6-((1R,5S,7S)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]decane-4-carbonyl)-8-methyl-3,8-diaza-bicyclo[3.2.1]octane-2,4-dione 
• 139527-59-6 (1R,5S,6R)-6-((1R,5S,7S)-10,10-Dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]decane-4-carbonyl)-3-[(R)-2-methoxymethoxy-1-(2-methoxy-6-methyl-phenyl)-ethyl]-8-methyl-3,8-diaza-bicyclo[3.2.1]octane-2,4-dione 
• 139527-62-1 <5R-(5α,8β,10β(3aR^*,6S^*,7aS^*),11β)>-1-<<5,7,8,9,10,11-hexahydro-4-methoxy-5-<(methoxymethoxy)methyl>-13-methyl-7-oxo-8,11-iminoazepino<1,2b>isoquinoline-10-yl>carbonyl>hexahydro-8,8-dimethyl-2,2-dioxo-3H-3a,6-methano-2,1-benzisothiazole 
• 139527-58-5 (1R,5S,6R)-6-((1R,5S,7S)-10,10-Dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]decane-4-carbonyl)-3-[(R)-2-hydroxy-1-(2-methoxy-6-methyl-phenyl)-ethyl]-8-methyl-3,8-diaza-bicyclo[3.2.1]octane-2,4-dione 
• 139527-63-2 <5R-(5α,8β,10β(3aR^*,6S^*,7aS^*),11β,11aβ)>-hexahydro-8,8-dimethyl-1-<<5,7,8,9,10,11,11a,12-octahydro-4-methoxy-5-<(methoxymethoxy)methyl>-13-methyl-7-oxo-8,11-iminoazepino<1,2-b>isoquinoline-10-yl>carbonyl>-2,2-dioxo-3H-3a,6-methano-2,1-benzis. 
• 139527-65-4 <5R-(5α,8β,10β,11β,11aβ)>-(-)-5,7,8,9,10,11,11a,12-octahydro-4-methoxy-5-<(methoxymethoxy)methyl>-13-methyl-7-oxo-8,11-iminoazepino<1,2-b>isoquinoline-10-carboxylic acid 

Downstream Products

• 84573-33-1 (-)-quinocarcin 
• 156246-79-6 (5R,7R,8S,10R,11R,11aS)-5-benzoyloxymethyl-7-cyano-10-hydroxymethyl-4-methoxy-13-methyl-5,7,8,9,10,11,11a,12-octahydro-8,11-iminoazepino<1,2-b>isoquinoline 
• 156246-78-5 C₃₀H₃₃N₃O₇ 
• 156246-77-4 (5R,7R,8S,10R,11R,11aS)-5-benzoyloxymethyl-7-cyano-4-methoxy-13-methyl-5,7,8,9,10,11,11a,12-octahydro-8,11-iminoazepino<1,2-b>isoquinoline-10-carboxylic acid 
• 84573-33-1 quinocarcin 

Relevant academic research and scientific papers

Synthetic Studies on Quinocarcin and Its Related Compounds. 4. Total Synthesis of Enantiomeric Pairs of Quinocarcin and 10-Decarboxyquinocarcin

The title synthesis was accomplished by featuring (i) aldol coupling of the 3-methylanisole 11 with 5-substituted- or 3,5-disubstituted- 2-formylpyrrolidine 4 or 5, (ii) highly diastereoselective reduction of 1,3-disubstituted isoquinolines 14 and 33 to c

The asymmetric synthesis of (-)-quinocarcin via a 1,3-dipolar cycloadditive strategy

Details of the asymmetric synthesis and complete structure elucidation of (-)-quinocarcin (1), an antitumor antibiotic that inhibits DNA (and in some systems RNA) synthesis, are reported. Key steps in the synthesis include the use of an auxiliary-controll