96256-64-3Relevant academic research and scientific papers
Aryl trifluoromethyl-1,2,3-triazoles
Meazza, G.,Zanardi, G.
, p. 199 - 206 (2007/10/02)
Diaryl-substituted trifluoromethyl-1,2,3-triazoles have been synthesised from aromatic azides and various substituted 1-aryl-3,3,3-trifluoro-1-propynes.The spectroscopic characteristics of the products and the regioselectivity of the reaction are discusse
Studies on Organic Fluorine Compounds. XLII. Synthesis and Reactions of Phenyltrifluoromethylacetylenes
Kobayashi, Yoshiro,Yamashita, Toshinori,Takahashi, Katsuhiro,Kuroda, Hisashi,Kumadaki, Itsumaro
, p. 4402 - 4409 (2007/10/02)
Phenyltrifluoromethylacetylene (4a) was synthesized by the pyrolysis of triphenylphosphonium α-(trifluoroacetyl)benzylide (3a), which was easily derived from benzyl halide (1a).This method can be used for the synthesis of 4-substituted-phenyltrifluoromethylacetylenes (4).The 1,3-dipolar reaction of 4 with diazomethane and phenyl azide proceeds readily to give trifluoromethylated pyrazoles and triazoles.Keywords - trifluoromethyl; acetylene; 1,3-dipolar reaction; intramolecular Wittig reaction; trifluoroacetylphosphonium ylide; pyrazole; diazomethane; phenyl azide
