Trt-Gly-ONB, also known as tert-butoxycarbonyl-glycine-ortho-nitrobenzyl, is a chemical compound that serves as a protecting group in peptide synthesis. It is a derivative of glycine, an amino acid, with a tert-butoxycarbonyl (Boc) group and an ortho-nitrobenzyl (ONB) group attached. The Boc group is used to protect the amino group of glycine, while the ONB group is used to protect the carboxylic acid group. Trt-Gly-ONB is crucial in the synthesis of peptides, as it allows for the stepwise addition of amino acids while preventing unwanted side reactions. The ONB group can be selectively removed under mild conditions, enabling the controlled deprotection and coupling of amino acids in the peptide chain.
The CAS Registry Mumber 96277-38-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,6,2,7 and 7 respectively; the second part has 2 digits, 3 and 8 respectively. Calculate Digit Verification of CAS Registry Number 96277-38: (7*9)+(6*6)+(5*2)+(4*7)+(3*7)+(2*3)+(1*8)=172 172 % 10 = 2 So 96277-38-2 is a valid CAS Registry Number.