96283-60-2Relevant academic research and scientific papers
Process for the fluorination of acrylic acid and derivatives thereof and novel fluorinated esters of 2,3-difluoropropionic acid
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, (2008/06/13)
Difluoropropionic acid and derivatives thereof are prepared by bringing elemental fluorine in the presence of a solvent into an addition reaction with appropriate acrylic acids or derivatives thereof. In this way, it is also possible to obtain novel fluorinated esters of 2,3-difluoropropionic acid.
Synthese von α-Fluoracrylsaeure und Derivaten
Gassen, K.-R.,Bielefeldt, D.,Marhold, A.,Andres P.
, p. 149 - 162 (2007/10/02)
Three new routes to derivatives of α-fluoracrylic acid, including a laboratory synthesis and a large-scale method, are reported.The processes are (i) addition of elementary fluorine to acrylic esters and subsequent elimination of HF; (ii) addition of difluorocarbene to isopropenyl methyl ether, oxidation via ring opening and dehalogenation; and (iii) "nitrofluorination" of 2,3-dichloropropene, hydrolysis and dechlorination.
