96286-49-6Relevant academic research and scientific papers
REACTIONS SRN1 EN SERIE HETEROCYCLIQUE: I - REACTIVITE DE SELS DE NITRO-5 TETRAHYDROOXAZINES-1,3
Crozet, Michel P.,Vanelle, Patrice
, p. 323 - 326 (1985)
Heterocyclic nitronate anions prepared from 3-ethyl-5-hydroxymethyl-5-nitrotetrahydro-1,3-oxazine are found to be suitable nucleophiles for SRN1 reactions.Base-promoted nitrous acid elimination from C-alkylation product gives rise to new tetrah
Copper-catalyzed alkene arylation with diaryliodonium salts
Phipps, Robert J.,McMurray, Lindsay,Ritter, Stefanie,Duong, Hung A.,Gaunt, Matthew J.
supporting information; experimental part, p. 10773 - 10776 (2012/08/07)
Alkenes and arenes represent two classes of feedstock compounds whose union has fundamental importance to synthetic organic chemistry. We report a new approach to alkene arylation using diaryliodonium salts and Cu catalysis. Using a range of simple alkenes, we have shown that the product outcomes differ significantly from those commonly obtained by the Heck reaction. We have used these insights to develop a number of new tandem and cascade reactions that transform readily available alkenes into complex arylated products that may have broad applications in chemical synthesis.
