96289-97-3Relevant academic research and scientific papers
Gram-Scale Preparation of Pd@PANI: A Practical Catalyst Reagent for Copper-Free and Ligand-Free Sonogashira Couplings
Yu, Lei,Han, Zhe,Ding, Yuanhua
, p. 2124 - 2129 (2016)
Palladium nanoparticles on the polyaniline (Pd@PANI) catalyst are now easily prepared on a gram scale through the oxidative polymerization of aniline in the presence of PdCl2 by using air as a clean oxidant. The material is found to be very stable and can be stored for more than one year without deactivation. Thus, it may become a commercial reagent in organic synthesis, depending on its application scopes. This article reported the first example of Pd@PANI-catalyzed Sonogashira couplings free of copper and ligands.
A Facile Method to Append Peptidal Side-Chains onto Steroidal Templates
Horwell, David C.,Lennon, Ian C.,Roberts, Edward
, p. 4225 - 4234 (2007/10/02)
Side-Chains corresponding to phenylalanine, tyrosine and tryptophan are introduced onto a steroid template in a highly efficient manner via a condensation of the appropriate lithium acetylide with a steroidal ketone.The subsequent acetylene functionality can be selectively reduced in the presence of a modified benzyl ether and steroid ring unsaturation.
Synthesis of 21-aryl and heteroaryl ethisterones and the corresponding A-ring substituted [2,3-d]isoxazoles
Kumar,Todaro
, p. 523 - 525 (2007/10/02)
Palladium(0) catalyzed coupling reaction of ethisterone [6; (17α)-17-hydroxypregn-4-en-20-yn-3-one] with aromatic/heteroaromatic halides gave C-21 substituted derivatives 7. Hydroxymethylation of the latter compounds followed by treatment with hydroxylami
