96303-99-0Relevant articles and documents
Catalytic asymmetric addition of alkylzinc and functionalized alkylzinc reagents to ketones
Jeon, Sang-Jin,Li, Hongmei,Garcia, Celina,LaRochelle, Lynne K.,Walsh, Patrick J.
, p. 448 - 455 (2007/10/03)
(Chemical Equation Presented) We describe our full report of the catalytic asymmetric addition of simple and functionalized dialkylzinc reagents to a broad range of saturated ketones and enones. The functionalized organozinc reagents contain esters, silyl
DIASTEREOFACE-DIFERENTIATING ADDITION OF ORGANOMETALLICS TOWARD CHIRAL α-KETOENAMINES
Fujisawa, Tamotsu,Watanabe, Makoto,Sato, Toshio
, p. 2055 - 2058 (2007/10/02)
The diastereoface-differentiating reaction of Grignard reagents or organolithium reagents toward chiral cyclic α-ketoenamines, prepared from the corresponding cycloalkane-1,2-dione and optically active pyrrolidine derivatives, was found to give, after hydrolysis, (R)- or (S)-α-hydroxycycloalkanones, respectively, in high enantiomeric excess.