96315-81-0Relevant academic research and scientific papers
1-Phenylisoquinoline larvicidal activity against Culex quinquefasciatus
Quevedo, Rodolfo,Baquero, Edwin,Quinones, Martha L.
experimental part, p. 1094 - 1100 (2012/09/08)
The larvicidal potential of several dopamine 1-phenylisoquinoline derivatives against Culex quinquefasciatus third instar larvae was investigated in a rational search for insecticides. The results showed that these isoquinolines presented moderate larvicidal activity, that the presence of a substituent is needed on carbon 1 for such activity to be presented and that it may be possible to develop novel insecticidal compounds having potential use in controlling insects by appropriate structural modification of 1-phenylisoquinolines. This article presents a possible structure-larvicidal activity relationship for isoquinolinic compounds.
Regioselectivity in isoquinoline alkaloid synthesis
Quevedo, Rodolfo,Baquero, Edwin,Rodriguez, Mario
experimental part, p. 1774 - 1778 (2010/06/13)
Regioselectivity in isoquinoline alkaloid synthesis is analyzed here. Our experiments have shown that substituents on the aromatic ring of the starting amine are determinant in isoquinoline synthesis. The use of dicyclohexylcarbodiimide in activating carb
