96386-94-6

Usage

Uses

Used in Pharmaceutical Industry:
(S)-Methyl 3-(benzyloxycarbonylamino)-5-methylhexanoate is used as a key intermediate for the synthesis of drugs targeting bacterial infections and cancer. Its role in the development of new pharmaceutical products is crucial, as it aids in the creation of effective treatments for these diseases.
Used in Medicinal Chemistry Research:
(S)-Methyl 3-(benzyloxycarbonylamino)-5-methylhexanoate serves as a building block in the research of various biologically active compounds. Its application in medicinal chemistry is significant, as it contributes to the discovery and development of novel drug candidates with potential therapeutic benefits.
Used in Drug Development:
(S)-Methyl 3-(benzyloxycarbonylamino)-5-methylhexanoate is employed in the development of new drugs, where its unique structure and properties can be leveraged to create innovative pharmaceutical products with improved efficacy and safety profiles.

Upstream product

• 118247-68-0 N-Benzyloxycarbonyl-L-Homoleucine 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 61-90-5 L-leucine 
• 148854-04-0 (C₈H₇O₂)(NHCHCOO)(CH₂C₃H₇)(CO₂C₂H₅) 
• 102123-81-9 (3-diazo-1-(S)-(2-methylpropyl)-2-oxopropyl)carbamic acid benzyl ester 
• 186581-53-3 diazomethane 
• 100869-06-5 3(S)-amino-5-methylhexanoic acid hydrochloride 
• 501-53-1 benzyl chloroformate 
• 2018-66-8 Z-Leu-OH 
• 748793-65-9 N-(4-hydroxy-1-isobutyl-4-methyl-3-oxopentyl)carbamic acid O-benzyl ester 
• 748793-55-7 (E)-2-hydroxy-2,7-dimethyloct-4-en-3-one 
• 590-86-3 isovaleraldehyde 
• 621-84-1 O-benzyl carbamate 

Downstream Products

• 118247-76-0 Z-β-homo-Leu-D-Asp(OBzl)-NHCH2CH2C6H5 
• 118247-70-4 (Benzyloxycarbonyl)-β-homo-L-leucyl-β-benzyl-L-aspartic acid 2-phenylethylamide 
• 118247-75-9 Z-β-homo-Leu-D-Asp(OBzl)-NHCH2C6H5 
• 118247-69-1 Z-β-homo-Leu-Asp(OBzl)-NHCH2C6H5 
• 118247-99-7 H-β-homo-Leu-Asp-NHCH2CH2C6H5 
• 118247-63-5 Boc-Trp-β-homo-Leu-Asp-Phe-NH2 
• 118333-37-2 Boc-Trp-β-homo-Leu-D-Asp-D-Phe-NH2 
• 118247-62-4 (tert-Butoxycarbonyl)-L-tryptophyl-β-homo-L-leucyl-L-aspartic acid 2-phenylethylamide 
• 118333-36-1 Boc-Trp-β-homo-Leu-D-Asp-NHCH2CH2C6H5 
• 118247-61-3 Boc-Trp-β-homo-Leu-Asp-NHCH2C6H5 
• 118333-35-0 Boc-Trp-β-homo-Leu-D-Asp-NHCH2C6H5 
• 118333-45-2 Z-β-homo-Leu-D-Asp(OBzl)-D-Phe-NH2 
• 118247-71-5 Z-β-homo-Leu-Asp(OBzl)-Phe-NH2 
• 118247-68-0 N-Benzyloxycarbonyl-L-Homoleucine 

Relevant academic research and scientific papers

Synthesis of enantiopure free and N-benzyloxycarbonyl-protected 3-substituted homotaurines from naturally occurring amino acids

Enantiopure N-benzyloxycarbonyl-protected and free 3-substituted homotaurines were synthesized from naturally occurring amino acids via N-benzyloxycarbonyl protection, Arndt-Eistert homologation, reduction, esterification with thioacetic acid, and oxidation with performic acid. The current method is a convenient, practical, and salt-free method for the synthesis of enantiopure 3-substituted homotaurine with moderate to good yields.

Synthesis of enantiopure free and N-benzyloxycarbonyl-protected 3-substituted homotaurines from naturally occurring amino acids

Enantiopure N-benzyloxycarbonyl-protected and free 3-substituted homotaurines were synthesized from naturally occurring amino acids via N-benzyloxycarbonyl protection, Arndt-Eistert homologation, reduction, esterification with thioacetic acid, and oxidation with performic acid. The current method is a convenient, practical, and salt-free method for the synthesis of enantiopure 3-substituted homotaurine with moderate to good yields.

Catalytic enantioselective conjugate addition of carbamates

Catalytic, asymmetric conjugate addition of carbamates to enoyl systems has been realized for the first time, providing a two-step access to virtually enantiopure N-protected β-amino acids. Copyright

Synthesis of gastrin antagonists, analogues of the C-terminal tetrapeptide of gastrin, by introduction of a β-homo residue

A series of analogues of Boc-Trp-Leu-Asp-Phe-NH2, a potent gastrin agonist, were synthesized by introducing a β-homo residue in the sequence. These compounds were tested in vivo on acid secretion, in the anesthetized rat, and for their ability

HYPOTENSIVE PEPTIDES AND THEIR USE

Oligopeptides of formula (I) STR1 (wherein R 1 CO--is an acyl group. But is an isobutyl or sec-butyl group and X is a variety of organic groups) and salts and esters thereof have valuable renin inhibitory activity.