96402-64-1

Usage

Uses

Used in Pharmaceutical Industry:
(4R)-3-(Phenylmethoxy)carbonyl-1,3-thiazolidine-4-carboxylic acid is used as a prodrug for its potential to convert into an active form within the body. This property allows it to be utilized in the development of medications that require activation post-administration for enhanced efficacy and targeted action.
Used in Anti-inflammatory Applications:
As a compound with potential anti-inflammatory properties, (4R)-3-(Phenylmethoxy)carbonyl-1,3-thiazolidine-4-carboxylic acid may be employed in the treatment of various inflammatory conditions. Its ability to modulate inflammatory responses could make it a valuable component in pharmaceutical formulations aimed at reducing inflammation and associated symptoms.
Used in Antioxidant Applications:
Given its potential antioxidant properties, (4R)-3-(Phenylmethoxy)carbonyl-1,3-thiazolidine-4-carboxylic acid could be used in formulations designed to combat oxidative stress and related conditions. Its role in neutralizing free radicals and protecting cells from damage may contribute to the development of health supplements and therapeutic agents.
Further research and testing are required to fully understand the potential uses and effects of (4R)-3-(Phenylmethoxy)carbonyl-1,3-thiazolidine-4-carboxylic acid, as its precise mode of action in biological systems is still under investigation.

Upstream product

• 519156-43-5 (R)-4-Mercaptomethyl-5-oxo-oxazolidine-3-carboxylic acid benzyl ester 
• 6968-11-2 N,N'-bis(benzyloxycarbonyl)-L-cystine 
• 501-53-1 benzyl chloroformate 
• 34592-47-7 L-thioproline 

Downstream Products

• 128019-17-0 3-(benzyloxycarbonyl)-N-tert.butyl-4(R)-thiazolidinecarboxamide 
• 127578-81-8 Z-Thiopro-oxazolidine 
• 120033-52-5 N-glycine benzyl ester 
• 120033-50-3 N-<carbonyl>glycine benzyl ester 
• 120033-51-4 N-glycine benzyl ester 

Relevant academic research and scientific papers

N-(5-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS

Disclosed are compounds having Formula (I) and the compositions and methods thereof for treating or preventing a viral infection mediated at least in part by a virus in the Flaviviridae family of viruses, wherein A, R2, m, R, V, W, T, Z, R

N-METHYL AMINO ACIDS

The present invention relates to a compound of formula (I) or (II), processes for preparing them, peptides including them and kits involving them.

An efficient synthesis of N-methyl amino acids by way of intermediate 5-oxazolidinones

N-Methyl amino acids occur in many natural products. Experimental strategies are presented for a unified approach to the synthesis of N-methyl derivatives through 5-oxazolidinones of the 20 common L-amino acids. The amino acids with reactive side chains that required protecting groups or devoted syntheses for side chain construction for N-methylation to proceed included serine, threonine, tyrosine, cysteine, methionine, tryptophan, asparagine, histidine, and arginine. The studies have provided improved methods for the preparation of N-methyl serine, threonine, and tyrosine. All 20 of the common L-amino acids are now available in suitable forms for solid or solution-phase peptide synthesis.

Thiazolidine compounds and therapeutic method

In one embodiment this invention provides novel thiazolidine compounds, such as 3-[R-(-)-3-benzyloxycarbonylthiazolidine-4-carbonyl]thiazolidine corresponding to the formula: STR1 An invention thiazolidine compound exhibits prolyl endopeplidase inhibitory

Synthesis of Peptides Containing S-(N-Alkylcarbamoyl)cysteine Residues, Metabolites of N-Alkylformamides in Rodents and in Humans

Hydrochloride salts of S-(N-methylcarbamoyl), S-(N-ethylcarbamoyl), and S-(N,N-dimethylcarbamoyl) derivatives of cysteine, N-acetylcysteine, and cysteinylglycine have been prepared.S-(N-Methylcarbamoyl)glutathione hydrochloride has also been synthesized.Protecting groups for amino and carboxylic acid functions were selected for their ability to solubilize the peptides in dichloromethane in which solvent the thiols were treated with alkyl isocyanates and with N,N-dimethylcarbamoyl chloride.Removal of S-(amidomethyl) protecting groups using mercury(II) acetate was found to cause some loss of N-(tert-butoxycarbonyl) groups.Elimination of disulfide was evident during coupling of disulfide derivatives of cysteine using mixed anhydride methods but not with a carbodiimide coupling agent.Mixed disulfide protections were reductively cleaved by propane-1,3-dithiol.Many of the deprotected S-carbamoyl amino acids and peptides are metabolites of the corresponding N-alkylformamides in rodents and in humans.