96449-89-7

Basic information

• Product Name: 1-(4-METHOXY-BENZYL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID
• Synonyms: 1-(4-METHOXY-BENZYL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID;AKOS BC-2632;1-[(4-methoxyphenyl)methyl]-5-oxo-3-pyrrolidinecarboxylic acid;5-keto-1-(4-methoxybenzyl)pyrrolidine-3-carboxylic acid;A3438/0145951;BAS 09589675;ChemDiv3_014153;IDI1_029951
• CAS NO: 96449-89-7
• Molecular Formula: C₁₃H₁₅NO₄
• Molecular Weight: 249.26
• Product Categories: Carboxylic Acids;Carboxylic Acids;Pyrrolidines
• Mol File: 96449-89-7.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(4-METHOXY-BENZYL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-METHOXY-BENZYL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID(96449-89-7)
• EPA Substance Registry System: 1-(4-METHOXY-BENZYL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID(96449-89-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 96449-89-7(Hazardous Substances Data)

Usage

Uses

1-(4-Methoxybenzyl)-5-oxopyrrolidine-3-carboxylic acid

Upstream product

• 2393-23-9 4-methoxy-benzylamine 
• 617-52-7 Dimethyl itakonate 
• 149505-71-5 methyl 1-[(4-methoxyphenyl)methyl]-5-oxopyrrolidine-3-carboxylate 
• 97-65-4 2-methylenesuccinic acid 

Downstream Products

• 1356699-97-2 4-(4-benzylpiperazine-1-carbonyl)-1-(4-methoxybenzyl)pyrrolidin-2-one 
• 304857-53-2 N-[3-(4-benzylpiperidin-1-yl)propyl]-5-oxo-N-phenylpyrrolidine-3-carboxamide 

Relevant articles and documents

Asymmetric Formal Synthesis of (+)-Catharanthine via Desymmetrization of Isoquinuclidine

Although (+)-catharanthine is an attractive alkaloid for both clinical research and organic synthetic chemistry, only a limited number of approaches for its catalytic asymmetric synthesis exist. Herein, we describe a novel strategy for synthesizing a chir

Inhibition of noroviruses by piperazine derivatives

There is currently an unmet need for the development of small-molecule therapeutics for norovirus infection. The piperazine scaffold, a privileged structure embodied in many pharmacological agents, was used to synthesize an array of structurally-diverse derivatives which were screened for anti-norovius activity in a cell-based replicon system. The studies described herein demonstrate for the first time that functionalized piperazine derivatives possess anti-norovirus activity. Furthermore, these studies have led to the identification of two promising compounds (6a and 9l) that can be used as a launching pad for the optimization of potency, cytotoxicity, and drug-like characteristics.

CYCLIC AMIDE COMPOUNDS, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF

A compound of the formula: wherein R1 is a hydrocarbon group, R2 is a hydrocarbon group having 2 or more carbon atoms, where R1 and R2 may in combination form, together with an adjacent nitrogen atom, a ring optionally having a substituent or substituents, R3 is a hydrocarbon group optionally having a substituent or substituents or a heterocyclic group optionally having a substituent or substituents, R4 is a hydrogen atom, a hydrocarbon group, a heterocyclic group and the like, E is a divalent chain hydrocarbon group and the like, G is CO or SO2, J is a nitrogen atom, a methine group and the like, and Q and R are each a divalent chain C1-3 hydrocarbon group and the like, and a salt thereof show a superior CCR5 antagonistic activity and are useful as agents for the prophylaxis or treatment of HIV infection of human peripheral blood mononuclear cells, particularly AIDS.