965-93-5

Basic information

• Product Name: Methyltrienolone
• Synonyms: METRIBOLONE;METHYLTRIENOLONE;17b-hydroxy-17-methylestra-4,9,11-trien-3-one;17A-METHYL-TRENBOLONE;R1881;(17S)-17-Hydroxy-17-methylestra-4,9,11-triene-3-one;17β-Hydroxy-17-methylestra-4,9,11-trien-3-one;RU-1881
• CAS NO: 965-93-5
• Molecular Formula: C19H24O2
• Molecular Weight: 284.39
• EINECS: 1592732-453-0
• Product Categories: Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;trenbolone series
• Mol File: 965-93-5.mol
• Article Data: 0

Chemical Properties

• Melting Point: 170°
• Boiling Point: 485.9 °C at 760 mmHg
• Flash Point: 206.3 °C
• Appearance: light yellow to yellow/
• Density: 1.17 g/cm³
• Vapor Pressure: 1.76E-11mmHg at 25°C
• Refractive Index: 1.597
• Storage Temp.: 2-8°C
• Solubility: DMSO: ≥10mg/mL
• PKA: 14.79±0.40(Predicted)
• CAS DataBase Reference: Methyltrienolone(CAS DataBase Reference)
• NIST Chemistry Reference: Methyltrienolone(965-93-5)
• EPA Substance Registry System: Methyltrienolone(965-93-5)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 965-93-5(Hazardous Substances Data)

Usage

Description

Methyltrienolone is an orally active anabolic-androgen steroid being a 17α-alkylated nandrolone (19-nortestosterone) derivative. It is not sold as a prescription drug and a dietary supplement due to its strong androgenic side effects and liver toxicity. However, it is often used as the reference point for in vitro biological activity for biochemical studies. It can bind strongly to the androgen receptor and can be used as an affinity label of the androgen receptor in the prostate and in prostatic tumors.

Chemical Properties

Pale Yellow Solid

Definition

ChEBI: A synthetic non-aromatisable androgen and anabolic steroid. It binds strongly to the androgen receptor and has therefore also been used as an affinity label for this receptor in the prostate and in prostatic tumors.

Biochem/physiol Actions

Androgen receptors (ARs) are nuclear hormone receptors/transcription factors. R1881, also known as methyltrienolone, is a synthetic androgen. It is the gold standard AR agonist.

References

https://en.wikipedia.org/wiki/Metribolone https://www.drugbank.ca/drugs/DB02998 https://pubchem.ncbi.nlm.nih.gov/compound/Methyltrienolone Kazlauskas R. (2010) Designer Steroids. In: Thieme D., Hemmersbach P. (eds) Doping in Sports: Biochemical Principles, Effects and Analysis. Handbook of Experimental Pharmacology, vol 195. Springer, Berlin, Heidelberg

InChI:InChI=1/C19H24O2/c1-18-9-7-15-14-6-4-13(20)11-12(14)3-5-16(15)17(18)8-10-19(18,2)21/h7,9,11,16-17,21H,3-6,8,10H2,1-2H3/t16-,17+,18+,19+/m1/s1