96558-72-4

Basic information

• Product Name: Benzene, 1,2,3-tribromo-4-nitro-
• Synonyms: 2,3,4-tribromo-aniline;tribromoaniline;1,2,3-Tribrom-4-nitro-benzol;2,3,4-tribromo-5-trifluoromethylsulfanyl-pyrrole;2,3,4-Tribrom-anilin;2,3,4-tribromo-5-trifluoromethylsulfanyl-1H-pyrrole;2,3,4-tribromonitrobenzene;Benzene, 1,2,3-tribromo-4-nitro-;1,2,3-tribromo-4-nitro-benzene
• CAS NO: 96558-72-4
• Molecular Formula: C6H2Br3NO2
• Molecular Weight: 359.799
• Mol File: 96558-72-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzene, 1,2,3-tribromo-4-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,2,3-tribromo-4-nitro-(96558-72-4)
• EPA Substance Registry System: Benzene, 1,2,3-tribromo-4-nitro-(96558-72-4)

Safety Data

• Hazardous Substances Data: 96558-72-4(Hazardous Substances Data)

Upstream product

• 608-21-9 1,2,3-tribromobenzene 
• 608-30-0 2,6-dibromoaniline 

Downstream Products

• 642-95-5 2,3,4-tribromoaniline 

Relevant articles and documents

Total synthesis of (±)-cis-trikentrin B via intermolecular 6,7-indole aryne cycloaddition and Stille cross-coupling

An efficient total synthesis of the annulated indole natural product (±)-cis-trikentrin B was accomplished by means of a regioselectively generated 6,7-indole aryne cycloaddition via selective metal-halogen exchange from a 5,6,7-tribromoindole. The unaffected C-5 bromine was subsequently used for a Stille cross-coupling to install the butenyl side chain and complete the synthesis. This strategy provides rapid access into the trikentrins and the related herbindoles, and represents another application of this methodology to natural products total synthesis. The required 5,6,7-indole aryne precursor was prepared using the Leimgruber-Batcho indole synthesis.