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6-Nitro-3-(p-tolyl)quinazolin-4(3H)-one is a chemical compound belonging to the quinazolinone class, characterized by a quinazoline core structure with a nitro group at the 6-position and a p-tolyl group at the 3-position. 6-nitro-3-(p-tolyl)quinazolin-4(3H)-one is known for its potential applications in medicinal chemistry, particularly as a precursor in the synthesis of various bioactive molecules. The p-tolyl group, which is a para-methylphenyl group, introduces steric and electronic effects that can significantly influence the compound's reactivity and pharmacological properties. The nitro group at the 6-position can be reduced to an amine, which is a common transformation in the synthesis of quinazolinone-based drugs. 6-nitro-3-(p-tolyl)quinazolin-4(3H)-one's structure and properties make it a valuable intermediate in the development of new therapeutic agents, especially in the areas of oncology and antiviral therapy.

966-96-1

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966-96-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 966-96-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 9,6 and 6 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 966-96:
(5*9)+(4*6)+(3*6)+(2*9)+(1*6)=111
111 % 10 = 1
So 966-96-1 is a valid CAS Registry Number.

966-96-1Downstream Products

966-96-1Relevant academic research and scientific papers

Discovery of molluscicidal and cercaricidal activities of 3-substituted quinazolinone derivatives by a scaffold hopping approach using a pseudo-ring based on the intramolecular hydrogen bond formation

Guo, Wei,Zheng, Lv-Yin,Li, Yong-Dong,Wu, Ren-Miao,Chen, Qiang,Yang, Ding-Qiao,Fan, Xiao-Lin

, p. 291 - 294 (2016)

Discovery of novel topological agents against Oncomelania hupensis snails and cercariae remains a significant challenge in current Schistosomiasis control. A pseudo-ring formed from salicylanilide by an intramolecular hydrogen bond led to the discovery of 3-substituted quinazolinone derivatives which showed a potent molluscicidal and cercaricidal activities.

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