96604-34-1

Basic information

• Product Name: (E)-3-(DIMETHYLAMINO)-1-[3-(TRIFLUOROMETHYL)PHENYL]-2-BUTEN-1-ONE
• Synonyms: (E)-3-(DIMETHYLAMINO)-1-[3-(TRIFLUOROMETHYL)PHENYL]-2-BUTEN-1-ONE;3-(dimethylamino)-1-[3-(trifluoromethyl)phenyl]but-2-en-1-one
• CAS NO: 96604-34-1
• Molecular Formula: C₁₃H₁₄F₃NO
• Molecular Weight: 257.25
• Mol File: 96604-34-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 56-58 °C
• Boiling Point: 296.6±40.0 °C(Predicted)
• Appearance: /
• Density: 1.163±0.06 g/cm3(Predicted)
• PKA: 5.47±0.70(Predicted)
• CAS DataBase Reference: (E)-3-(DIMETHYLAMINO)-1-[3-(TRIFLUOROMETHYL)PHENYL]-2-BUTEN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-(DIMETHYLAMINO)-1-[3-(TRIFLUOROMETHYL)PHENYL]-2-BUTEN-1-ONE(96604-34-1)
• EPA Substance Registry System: (E)-3-(DIMETHYLAMINO)-1-[3-(TRIFLUOROMETHYL)PHENYL]-2-BUTEN-1-ONE(96604-34-1)

Safety Data

• Hazardous Substances Data: 96604-34-1(Hazardous Substances Data)

Upstream product

• 349-76-8 3'-(trifluoromethyl)acetophenone 
• 19429-85-7 N,N-dimethylacetamide diethyl acetal 
• 18871-66-4 N,N-dimethylacetamide dimethyl acetal 

Downstream Products

• 112778-81-1 4-methyl-2-<3-(trifluoromethyl)phenyl>pyrimido<1,2-a>benzimidazole 
• 112778-80-0 2-methyl-4-<3-(trifluoromethyl)phenyl>pyrimido<1,2-a>benzimidazole 

Relevant articles and documents

A simple synthesis of dimethyl 2-[(Z)-3-amino-1-oxo-1-(substituted)but-2-en-2-yl]fumarates: Potential intermediates in the synthesis of polysubstituted five- and six-membered heterocycles

In this communication, a simple synthesis of dimethyl 2-[(Z)-3-amino-1-oxo-1-(substituted)but-2-en-2-yl] fumarates is described. Methyl ketones were transformed by treatment with N,N-dimethylacetamide dimethyl acetal (DMADMA) into 3-dimethylamino-1-(subst

A Simple Regioselective Synthesis of Pyrimidobenzimidazoles

2-Aminobenzimidazoles were reacted with enaminones in acetic acid to give pyrimidobenzimidazoles.With a substituted enaminone only one regioisomer was obtained.Structural assignments based on nmr and uv spectroscopy are presented.Possible pathways