96632-04-1

Basic information

• Product Name: methyl (Z)-7-(p-tolylsulphonyloxy)hept-5-enoate
• Synonyms: methyl (Z)-7-(p-tolylsulphonyloxy)hept-5-enoate
• CAS NO: 96632-04-1
• Molecular Weight: 312.387
• Mol File: 96632-04-1.mol

Chemical Properties

• CAS DataBase Reference: methyl (Z)-7-(p-tolylsulphonyloxy)hept-5-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (Z)-7-(p-tolylsulphonyloxy)hept-5-enoate(96632-04-1)
• EPA Substance Registry System: methyl (Z)-7-(p-tolylsulphonyloxy)hept-5-enoate(96632-04-1)

Safety Data

• Hazardous Substances Data: 96632-04-1(Hazardous Substances Data)

Upstream product

• 50781-90-3 methyl 7-(tetrahydro-2'H-pyran-2'-yloxy)hept-5-ynoate 
• 50781-91-4 methyl 7-hydroxy-5-heptynoate 
• 34506-49-5 7-(tetrahydro-2'H-pyran-2'-yloxy)hept-5-ynoic acid 
• 34506-48-4 6-<(tetrahydropyranyl)oxy>-4-hexynenitrile 
• 34520-18-8 6-chloro-2-hexyn-1-yl 2-tetrahydropyranyl ether 
• 64244-45-7 methyl (Z)-7-hydroxy-5-heptenoate 
• 98-59-9 p-toluenesulfonyl chloride 

Relevant articles and documents

ALKYNE-COBALT COMPLEXES AS PROSTAGLANDIN SYNTHONS. III. IMPROVED ROUTE TO METHYL (Z)-NON-5-EN-8-YNOATE AND SYNTHESIS OF A NEW PROSTAGLANDIN E2 ANALOGUE.

Hydrogenation of methyl 7-hydroxyhept-5-ynoate followed by formation of the p-toluene-p-sulphonate ester and reaction with ethynylmagnesium bromide leads to an improved synthesis of methyl Z-non-5-en-8-ynoate, whose hexacarbonyldicobalt complex reacts smoothly with 2,5-dihydrofuran.Conventional "mixed cuprate" methodology is used to add the "β"-side chain producing a novel, but biologically inactive bicyclic prostaglandin E2 analogue.Cobalt carbonyl complexed selectively with the terminal triple bond of a 1,3-diyne but the product proved unsuitable for similar synthetic elaboration.