96638-28-7

Basic information

• Product Name: RICIN, A CHAIN
• Synonyms: RICIN, A CHAIN;ricin(castor-oilplanta-chainproteinmoietyreduced);LECTIN FROM RICINUS COMMUNIS RICIN,*A CH AIN;ricin a chain from ricinus communis (castor bean);ricin A
• CAS NO: 96638-28-7
• Molecular Formula: NULL
• Molecular Weight: 0
• Product Categories: Ricinus communis (Castor bean);Glycan Recognizing Proteins;Lectins and Lectin Antibodies;Ricinus communis (Castor bean)Immune Cell Signaling and Blood;Immune System Regulation;Lectins
• Mol File: 96638-28-7.mol
• Article Data: 0

Chemical Properties

• Appearance: /buffered aqueous glycerol solution
• Storage Temp.: 2-8°C
• CAS DataBase Reference: RICIN, A CHAIN(CAS DataBase Reference)
• NIST Chemistry Reference: RICIN, A CHAIN(96638-28-7)
• EPA Substance Registry System: RICIN, A CHAIN(96638-28-7)

Safety Data

• Hazard Codes: T+
• Statements: 26/27/28-42/43
• Safety Statements: 23-28-36/37-45
• RIDADR: UN 3172 6.1/PG 3
• WGK Germany: 1
• HazardClass: 6.1(a)
• PackingGroup: I
• Hazardous Substances Data: 96638-28-7(Hazardous Substances Data)

Usage

Biochem/physiol Actions

Ricin A chain inactivates the 60?S ribosomal subunit of eukaryotic cells, inhibiting protein synthesis. This toxic activity is independent of the presence of the B chain of ricin.

Purification Methods

Ricin (toxin from Castor bean Ricinus communis) [A chain 96638-28-7, B chain 96638-29-8] Mr ~30,000, amorphous. Crude ricin, obtained by aqueous extraction and (NH4)2SO4 precipitation, is chromatographed on a galactosyl-Sepharose column with sequential elution of pure ricin. The second peak is due to ricin agglutinin. [Simmons & Russell Anal Biochem 146 206 1985.] It is an inhibitor of protein synthesis. EXTREMELY DANGEROUS, USE EXTREME CARE [instructions accompany product].