96683-92-0

Upstream product

• 98-01-1 furfural 
• 96683-95-3 2-((ethoxycarbonyl)(furan-2-ylmethyl)amino)acetic acid 
• 96683-94-2 Potassium; (ethoxycarbonyl-furan-2-ylmethyl-amino)-acetate 
• 96683-93-1 ethyl 2-[[N-ethoxycarbonyl-N-(furan-2-yl)methyl]amino]acetate 
• 41681-88-3 ethyl 2-[((furan-2-yl)methyl)amino]acetate 
• 617-89-0 furan-2-ylmethanamine 

Downstream Products

• 96683-21-5 4-(2-methoxyphenyl)-6-methyl-4,5,6,7-tetrahydrofuro<2,3-c>pyridine 
• 96683-20-4 4-(4-methoxyphenyl)-6-methyl-4,5,6,7-tetrahydrofuro<2,3-c>pyridine hydrochloride 
• 96683-44-2 4-(2-chlorophenyl)-2,6-dimethyl-4,5,6,7-tetrahydrofuro<2,3-c>pyridine hydrochloride 
• 107428-76-2 4-(3,4-dimethoxyphenyl)-6-methyl-4,5,6,7-tetrahydrofuro<2,3-c>pyridine hydrochloride 
• 107428-64-8 6-methyl-4-phenyl-4,5,6,7-tetrahydrofuro<2,3-c>pyridine maleate 
• 732207-01-1 2-methyl-4-(p-methoxyphenyl)-4,5,6,7-tetrahydro-furano[2,3-c]pyridine 

Relevant academic research and scientific papers

PROCESS FOR PREPARING FOSTEMSAVIR

A method for the preparation of a compound of Formula IV wherein P1 is H or a suitable protecting group, comprising preparation of a compound of Formula I wherein P2 is H or a suitable protecting group and R1 is H or Csub

6-(tert-butoxycarbonyl) octahydro-furo [2,3-c] pyridine-4-carboxylic acid synthetic method

The present invention relates to a 6-(tert-butoxycarbonyl) octahydro-furo [2,3-c] pyridine-4-carboxylic acid synthetic method and mainly solves a technical problem that currently no suitable industrial synthetic method exists. The synthetic method comprises ten steps as follows: firstly a compound 1 is subjected to a reductive amination with a furfural to obtain a compound 2; then the compound 2 is subjected to alkylation to produce a compound 3; the compound 3 is hydrolyzed to obtain a hydrolyzate 4; the hydrolyzate 4 is subjected to an intramolecular Friedel-Crafts reaction to obtain a compound 5; the compound 5 is subjected to a hydrogenation reduction to obtain a compound 6; a trifluoromethanesulfonyl is bond to a ketone group of the compound 6 to obtain a compound 7; a carbonyl group inserted to the compound 7 to obtain a compound 8; the compound 8 is subjected to a double bond hydrogenation reduction to obtain a compound 9; the compound 9 is subjected to ethoxycarbonyl removing by a strong acid; and the ethoxycarbonyl removed compound 9 is reacted with a Boc anhydride to obtain a final compound 11. The reaction formulas are described as follows.

HETEROARYL DERIVATIVES

The present invention relates to a compound represented by the following formula [1] or a pharmaceutically acceptable salt thereof. In the formula [1], either of X and Y is CH and the other is oxygen or sulfur; R is hydrogen, etc.; Z is hydrogen, etc.; Ar

4-phenyl-tetrahydro-furano-pyridines and anti-depressant pharmaceutical compositions containing same

The invention relates to 4-phenyl-tetrahydro-furano-pyridines of the formulas STR1 wherein R1 to R5 are variously defined. The compounds of the invention are intended to be used as anti-depressants with, in particular, thymoleptic an

Acid-catalysed Cyclization of 1-Aryl-2-thienylmethyl- and 1-Aryl-2-furfurylaminoethanols via Spiro Intermediates

1-(4-Chlorophenyl)-2-(5-chloro-2-thienylmethyl)methylaminoethanol (7) reacts in trifluoroacetic acid to give the spirothiolenone (10) and the two isomeric tetrahydrothieno- and pyridines (8) and (9).Treatment of 1-aryl-2-furfurylaminoethanol