967-38-4

Upstream product

• 1925-61-7 benzyl 4-ethyl-3,5-dimethylpyrrole-2-carboxylate 
• 100-51-6 benzyl alcohol 
• 2199-47-5 ethyl 3,5-dimethyl-4-ethylpyrrole-2-carboxylate 

Downstream Products

• 52459-87-7 benzyl 3-methyl-4-ethyl-5-t-butyloxycarbonyl-pyrrole-2-carboxylate 
• 23466-29-7 4-ethyl-3-methyl-pyrrole-2-carboxylic acid 
• 13219-65-3 5-chlorocarbonyl-4-ethyl-3-methyl-pyrrole-2-carboxylic acid benzyl ester 
• 83089-91-2 benzyl 3-ethyl-2-iodo-4-methylpyrrole-5-carboxylate 
• 130693-50-4 8-(2-chloroethyl)-1,4,6-triethyl-1',2,3,5,7,8'-hexamethyl-ac-biladiene dihydrobromide 
• 130693-51-5 1-(2'-chloroethyl)-4,6,8-triethyl-1',2,3,5,7,8'-hexamethyl-ac-biladiene dihydrobromide 
• 130693-48-0 4-(2'-chloroethyl)-1,6,8-triethyl-1,2,3,5,7,8'-hexamethyl-ac-biladiene dihydrobromide 
• 52459-98-0 benzyl 5'-t-butoxycarbonyl-3,4'-diethyl-4,3'-dimethyl-2,2'-dipyrrylmethane-5-carboxylate 
• 33317-09-8 benzyl 5'-t-butoxycarbonyl-3'-ethyl-4-(2-methoxycarbonylethyl)-3,4'-dimethylpyrromethane-5-carboxylate 
• 21059-15-4 mesobiliverdin IXα 
• 108802-20-6 C₂₉H₃₆N₂O₆ 
• 108785-16-6 C₃₁H₄₀N₂O₆ 
• 83113-34-2 benzyl 3,3'-diethyl-4,4'-dimethyl-5'-t-butoxycarbonyldipyrromethane-5-carboxylate 
• 96246-74-1 benzyl 4-ethyl-5-formyl-3-methylpyrrole-2-carboxylate 

Relevant academic research and scientific papers

Synthesis and spectra of substituted pyrroles

A procedure was developed for synthesis of α-unsubstituted pyrroles with a desired arrangement of substituents in the β-positions.

Porphyrins with Exocyclic Rings. Part 3. A Reassessment on the Utility of Cyclopentapyrroles in the Synthesis of Porphyrin Molecular Fossils. Preparation of Three Type II Porphyrins Related to Deoxophylloerythroetioporphyrin (DPEP)

The utility of cyclopentapyrroles in porphyrin synthesis has been reinvestigated.A 6-oxocyclopentapyrrole 18 was prepared by cyclization of the propanoyl chloride sidechain of an α-unsubstituted pyrrole 17d in the presence of tin(IV) chloride.Subsequent reduction with sodium borohydride afforded the corresponding 6-hydroxy compound 10 and further acid catalyzed condensation with α-unsubstituted pyrroles 11a and 11b gave the novel 6-pyrrolylcyclopentapyrroles 22a and 22b in excellent yields.Attempts to prepare deoxophylloerythroetioporphyrin (DPEP; 2), a widespread sedimentary porphyrin molecular fossil, from these dipyrrolic intermediates using the tripyrrene-a,c-biladiene route were unsuccessful.However, the synthesis of three related meso,β-ethanoporphyrins using the MacDonald condensation was successfully carried out in moderate to good yields.Retention of an sp3 hybridized carbon bridge at the cyclopentene ring fusion site of the intermediary open chain tetrapyrroles appears to be crucial during macrocycle formation, as this diminishes the steric repulsion between the peripheral substituents and the carbocyclic ring.

Synthesis and Characterisation of the C30-De-ethylaetioporphyrin Present in Petroleum

The four de-ethyl analogues of the relatively ubiquitous and biogenetically significant petroporphyrin aetioporphyrin III (3a-d) have been synthesized utilising the ac-biladiene route.A reversed-phase HPLC method of separating a mixture of the four synthe