96737-93-8 Usage
Uses
5β-Pregnan-3α-ol-20-one-d4 is a labelled analogue of 5β-Pregnan-3α-ol-20-one (P711300), which is a hyponotic-anaesthetic agent. It is also an intermediate in synthesizing Pregnanediol-d5 3α-O-β-D-Glucuronide (P705142), which is a glucuronide conjugate of Pregnanediol (P705130). Levels of Pregnanediol 3α-O-β-D-Glucuronide can be used to monitor the reproductive status of dairy cows. 3α-O-β-D-Glucuronide can be used (as an alternative to creatine) as a reference to adjust other hormonal markers in study of urinary hormonal profiles in the human menstrual cycle.
Check Digit Verification of cas no
The CAS Registry Mumber 96737-93-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,6,7,3 and 7 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 96737-93:
(7*9)+(6*6)+(5*7)+(4*3)+(3*7)+(2*9)+(1*3)=188
188 % 10 = 8
So 96737-93-8 is a valid CAS Registry Number.
96737-93-8Relevant articles and documents
The mechanism of enzymic hydroxyl group removal from C-21 of tetrahydrodeoxycorticosterone
Holland, Herbert L.,Riemland, Elly
, p. 981 - 983 (2007/10/02)
The C-21 hydroxyl group of C-17- and C-21-deuterium labelled tetrahydrodeoxycorticosterone is removed by the anaerobic intestinal bacterium Eubacterium lentum ATCC 25559 with retention of deuterium label at C-17α and loss of one of the two deuterium atoms originally present at C-21.Dehydroxylation at C-21 proceeds with an apparent primary kinetic isotope effect, KH/KD at C-21 of 2.6.These data suggest a route for C-21 dehydroxylation involving a C-20(21)-enediol intermediate.
