96738-19-1

Basic information

• Product Name: (1R,3R,8aR)-2-Oxo-1-phenylacetylamino-1,8a-dihydro-2H,3H-8-thia-2a-aza-cyclobuta[b]naphthalene-3-carboxylic acid methyl ester
• Synonyms: (1R,3R,8aR)-2-Oxo-1-phenylacetylamino-1,8a-dihydro-2H,3H-8-thia-2a-aza-cyclobuta[b]naphthalene-3-carboxylic acid methyl ester
• CAS NO: 96738-19-1
• Molecular Weight: 382.44
• Mol File: 96738-19-1.mol

Chemical Properties

• CAS DataBase Reference: (1R,3R,8aR)-2-Oxo-1-phenylacetylamino-1,8a-dihydro-2H,3H-8-thia-2a-aza-cyclobuta[b]naphthalene-3-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,3R,8aR)-2-Oxo-1-phenylacetylamino-1,8a-dihydro-2H,3H-8-thia-2a-aza-cyclobuta[b]naphthalene-3-carboxylic acid methyl ester(96738-19-1)
• EPA Substance Registry System: (1R,3R,8aR)-2-Oxo-1-phenylacetylamino-1,8a-dihydro-2H,3H-8-thia-2a-aza-cyclobuta[b]naphthalene-3-carboxylic acid methyl ester(96738-19-1)

Safety Data

• Hazardous Substances Data: 96738-19-1(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 96738-17-9 (1R,3R,8aR)-2-Oxo-1-phenylacetylamino-1,8a-dihydro-2H,3H-8-thia-2a-aza-cyclobuta[b]naphthalene-3-carboxylic acid benzhydryl ester 

Downstream Products

• 69810-49-7 (R)-((S)-2-Oxo-3-phenylacetylamino-azetidin-1-yl)-phenyl-acetic acid methyl ester 

Relevant articles and documents

Synthesis of Tricyclic Cephalosporins

Cephalosporin 3'-triphenylphosphonium ylide (1) reacted with acrylaldehyde to give the C-3,C-4 tricyclic compound (3), while the sulphoxide of the ylide (1) upon similar treatment gave the C-2,C-3 tricyclic compound (4) which was converted into the ring-fused analogue (7) of nocardin; desulphurization of this compound afforded the nocardicin nucleus (10).