96740-79-3Relevant academic research and scientific papers
CHARACTERIZATION OF NEW OXIDATION PRODUCTS OF THE PERCHLORATE SALT OF THE METHADONE METABOLITE, (+/-)-2-ETHYLIDENE-1,5-DIMETHYL-3,3-DIPHENYLPYRROLIDINE (EDDP)
Abbott, Frank S.,Slatter, J. Gregory,Kang, Gun Il
, p. 245 - 248 (2007/10/02)
The oxidation of (+/-)-2-ethyl-1,5-dimethyl-3,3-diphenylpyrrolinium perchlorate (1, EDDP) with m-chloroperbenzoic acid (MCPBA) afforded diastereomeric 2-(4',4'-diphenylheptan-5'-one-2'-yl)-oxaziridine (2), 4,4-diphenyl-2,5-heptadione (3), and the known compounds 2-ethyl-5-methyl-3,3-diphenyl-1-pyrroline (5, EMDP) and 1,5-dimethyl-3,3-diphenylpyrrolidone (4, DDP). 13C and 1H NMR results for the new compounds and mechanisms for their formation are discussed.
