96776-05-5Relevant academic research and scientific papers
Studies towards the design and synthesis of novel 1,5-diaryl-1h-imidazole-4-carboxylic acids and 1,5-diaryl-1h-imidazole-4-carbohydrazides as host ledgf/p75 and hiv-1 integrase interaction inhibitors
Bode, Moira L.,Fish, Muhammad Q.,Mabel Coyanis, E.,Rashamuse, Thompho J.
, (2021/10/25)
Two targeted sets of novel 1,5-diaryl-1H-imidazole-4-carboxylic acids 10 and carbohy-drazides 11 were designed and synthesized from their corresponding ester intermediates 17, which were prepared via cycloaddition of ethyl isocyanoacetate 16 and diarylimi
Synthesis and biological relationships of 3′,6-substituted 2-phenyl-4-quinolone-3-carboxylic acid derivatives as antimitotic agents
Lai, Ya-Yun,Huang, Li-Jiau,Lee, Kuo-Hsiung,Xiao, Zhiyan,Bastow, Kenneth F.,Yamori, Takao,Kuo, Sheng-Chu
, p. 265 - 275 (2007/10/03)
As part of a continuing search for potential anticancer drug candidates in the 2-phenyl-4-quinolone series, 3′,6-substituted 2-phenyl-4-quinolone-3- carboxylic acid derivatives and their salts were synthesized and evaluated. Preliminary screening showed t
Substituted 2-phenyl-4-quinolone-3-carboxylic acid compounds and their use as antitumor agents
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Page/Page column 6, (2008/06/13)
Substituted 2-phenyl-4-quinolone-3-carboxylic acid derivatives and their salts were synthesized. The results of preliminary screening revealed that these compounds are potent in killing solid tumor cancers.
Reaction of Sulphuryl Chloride with Some Schiff Bases
Dhar, Durga N.,Gupta, Sudha R.
, p. 533 - 535 (2007/10/02)
The reaction of sulphuryl chloride with schiff bases has been studied.In each case, pure crystalline products have been isolated, and their structures elucidated on the basis of IR, PMR and mass spectral data.A plausible mechanism is advanced for the formation of observed products.
