96783-89-0Relevant academic research and scientific papers
Synthesis of some unique carbamate derivatives bearing 2-furoyl-1-piperazine as a valuable therapeutic agents
Abbasi, Muhammad Athar,Hussain, Ghulam,Aziz-Ur-Rehman,Siddiqui, Sabahat Zahra,Ali Shah, Syed Adnan,Lodhi, Muhammad Arif,Ali Khan, Farman,Ashraf, Muhammad,Qurat-Ul-Ain,Ahmad, Irshad,Malik, Rabia,Shahid, Muhammad,Mushtaq, Zahid
, p. 159 - 169 (2017/04/01)
The aim of the research work was to synthesize different biologically active carbamate derivatives bearing 2-furoyl-1piperazine and having modest toxicity. The synthesis was completed as a multiple sequence. The structural confirmation of all the synthesized compounds was obtained by EI-MS, IR and 1H-NMR spectral data. The enzyme inhibition and antibacterial potential of the synthesized compounds was evaluated. To find the utility of the prepared compounds as possible therapeutic agents their cytotoxicity was also checked. All the compounds were active against acetylcholinesterase enzyme, especially 12 and 14 showed very good inhibitory potential relative to Eserine, a reference standard. Almost all the compounds showed good activities against both Gram-positive and Gram-negative bacterial strains.
Nitrogen-containing aromatic derivatives
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, (2008/06/13)
Compounds represented by the following general formula: [wherein Ag is an optionally substituted 5- to 14-membered heterocyclic group, etc.; Xg is —O—, —S—, etc.; Yg is an optionally substituted C6-14 aryl group, an optionally substituted 5- to 14-membered heterocyclic group, etc.; and Tg1 is a group represented by the following general formula: (wherein Eg is a single bond or —N(Rg2)—, Rg1 and Rg2 each independently represent a hydrogen atom, an optionally substituted C1-6 alkyl group, etc. and Zg represents a C1-8 alkyl group, a C3-8 alicyclic hydrocarbon group, a C6-14 aryl group, etc.)], salts thereof or hydrates of the foregoing.
Herbicidal agents containing photosynthesis-inhibiting herbicides in combination with carbamate derivatives
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, (2008/06/13)
A herbicidal composition comprising a herbicidally effective among of (a) a photosynthesis-inhibiting herbicidally active compound, and (b) a synergistically effective amount of a carbamate derivative of the formula (II) STR1 in which R1 is alk
