96845-42-0

Upstream product

• 96845-35-1 (R)-3-((1R,3aR,4S,7aR)-4-Benzyloxy-7a-methyl-octahydro-inden-1-yl)-butyraldehyde 
• 96845-41-9 (2S,4R)-4-((1R,3aR,4S,7aR)-4-Benzyloxy-7a-methyl-octahydro-inden-1-yl)-1-(2-methyl-oxiranyl)-pentan-2-ol 
• 96845-40-8 (S)-6-[(R)-2-((1R,3aR,4S,7aR)-4-Benzyloxy-7a-methyl-octahydro-inden-1-yl)-propyl]-4-iodomethyl-4-methyl-[1,3]dioxan-2-one 
• 96845-39-5 Carbonic acid (S)-1-[(R)-2-((1R,3aR,4S,7aR)-4-benzyloxy-7a-methyl-octahydro-inden-1-yl)-propyl]-3-methyl-but-3-enyl ester tert-butyl ester 

Relevant academic research and scientific papers

A convergent route to calcitriol lactone via reductive cleavage of an enantiopure glycidyl ether

Reductive cleavage of the ((1-methyl-1-methoxy)ethyl) ether of (S)-2-methylglycidol with lithium 4,4'-di-6-butylbiphenylide, addition of aldehyde 3 to the resulting β-lithioalkoxide, followed by acidic hydrolysis, yields the advanced (23S,25R)-calcitriol