96854-24-9Relevant academic research and scientific papers
Process for a phenylthiobutyl-isoquinoline and intermediates therefor
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, (2008/06/13)
The present invention relates to a new method for making compounds of formula and intermediates for making compounds of formual II. The compounds of this invention are useful intermediates for the manufacture of pharmacologically active compounds suitable
Stereocontrolled Construction of Substituted Pyrrolidines based on Intramolecular Protodesilylation Reaction. Enantiospecific Synthesis of (-)-Kainic Acid and (+)-Allokainic Acid from L-Serine
Hatakeyama, Susumi,Sugawara, Kazutoshi,Takano, Seiichi
, p. 125 - 127 (2007/10/02)
Novel stereocontrolled enantiospecific syntheses of (-)-kainic acid and (+)-allokainic acid have been achieved starting from L-serine via two modes of C-2 and C-3 side chain-directed intramolecular protodesilylations of 4-(trimethylsilylmethyl)ethylidenepyrrolidines.
Enantiospecific synthesis of R- and S-5,6-dihydroxy-2-(N,N-di-n-propylamino)tetralins from serine
Baxter,Murray,Taylor
, p. 2331 - 2334 (2007/10/02)
The first enantiospecific synthesis of 5,6-dihydroxy-2-(N,N-di-n-propylamino)tetralin [5,6-(HO)2DPAT] is reported. Starting from D- or L-serine either enantiomer is readily available in high optical purity.
Synthesis and absolute configuration of wybutine, the fluorescent minor base from phenylalanine transfer ribonucleic acids
Itaya,Mizutani,Iida
, p. 1407 - 1414 (2007/10/02)
The phosphonium chloride 6 having an optically active amino acid moiety was synthesized from (S)-serine benzyl ester tosylate (2b) through a six-step route. The utility of 6 as a reagent for the Wittig reaction was exemplified in the olefination with benz
