96856-70-1

Upstream product

• 107-25-5 methoxyethene 
• 933-00-6 p-methylbenzenesulfenyl chloride 

Downstream Products

• 95349-75-0 4-p-tolylthio-1,1,3-trimethoxybutane 
• 134903-61-0 2-methyl-4,6-dimethoxy-7-(p-methylphenylthio)hept-1-ene 
• 110792-98-8 4-p-tolylthio-1,3-dimethoxybutane 
• 95349-74-9 4-p-tolylthio-3-methoxybutan-1-al 
• 125631-48-3 5-methoxy-6-p-tolylthiohexen-2-al-1 
• 103200-43-7 (2R,6S)-2-(1-Methoxy-2-p-tolylsulfanyl-ethyl)-6-methyl-cyclohexanone 
• 50397-67-6 methyl 2-(p-tolylthio)acetate 
• 103200-22-2 erythro-2-<1-Methoxy-2-(4-methylphenylthio)-ethyl>-cyclohexanone 
• 103200-22-2 threo-2-<1-Methoxy-2-(4-methylphenylthio)-ethyl>-cyclohexanone 
• 359701-09-0 4,6-dimethoxy-5,5-dimethyl-7-(p-tolylthio)hept-1-ene 

Relevant academic research and scientific papers

Arylsulfenyl chloride mediated coupling of three nucleophilic fragments with the formation of two c= bonds

The sequence of reactions ArSCl + vinyl ether-I + vinyl ether-II + organomagnesium reagents has been developed as a convergent protocol for assembling polyfunctional cokounds from simple precursors.

Polyfunctional compounds containing the 4,6-dialkoxy-7-arylthioheptene moiety as synthetically useful intermediates. The course of Lewis acid-induced transformations

Data on the selectivity of the Lewis acids induced transformations of the title compounds are presented, and the routes leading to formation of products containing either cyclohexane or 1,3-diene units are described.

A One-Pot Synthesis of β-C-Glucopyranosides from exo-Glucal, p-Tolylsulfenyl Chloride, an α-Methoxyalkene, and an External Nucleophile

(Matrix Presented) β-C-Glycosides were synthesized in one-pot experiments using the following sequence of four reactions: (i) addition of p-TolSCI to an α-methoxyalkene, (ii) generation of the episulfonium ion from a β-(arylsulfanyl)alkyl chloride, (iii)

Selectivity of the Lewis acid-induced transformations of polyfunctional compounds containing a 4,6-dialkoxy-7-(arylthio)heptene moiety

The interaction of the title adducts with Lewis acids may proceed as an attack at either β-alkoxy or δ-alkoxy group to the arylthio substituent leading to the formation of substituted cyclohexane or 1,3-diene derivatives, respectively.

Reactions of nitronates derived from simple nitro alkanes with some thio-stabilized cationic intermediates

Trimethylsilyl and DBU nitronates derived from nitromethane and nitropropanes do not undergo C-alkylation by episulfonium (ESI) or thiophanium (TPI) cationic intermediates. The above-mentioned derivatives of 1-nitropropane react with ESI and TPI to give the corresponding products of O-alkylation of 1-chloro-1-oxyiminopropane. The reactions of DBU nitronates derived from nitromethane and 2-nitropropane with ESI or TPI proceed as O-alkylation followed by standard fragmentation of the initially formed nitronate intermediates to give methyl (4-tolylthio)acetate or methyl 2,2-dimethyl-3-methyloxy-(4-tolylthio)butanoate respectively.

Tandem sequence of ArSCl initiated AdE reactions resulting in formation of two C-C bonds

A one-pot procedure for the sequence of reactions between arylsulfanyl chloride, vinyl ether-I, vinyl ether-II and organomagnesium reagents has been developed for assembling polyfunctional compounds from simple precursors. 2,3-Dihydropyran and various vin

REACTION SEQUENCE ARYLSULFENYL CHLORIDE + ALKOXYALKENE-I + ALKOXYALKENE-II + ALLYLMAGNESIUM OR BORON DERIVATIVES AS A NEW METHOD FOR THE CONTROLLED SYNTHESIS OF POLYFUNCTIONAL DERIVATIVES

A new method is proposed for the controlled synthesis of polyfunctional compouds with formation of two new carbon-carbon bonds; the method is based on the following reaction sequence, which can be carried out in a single flask: addition of ArSCl to vinyl ether I, reaction of the resultant adduct with vinyl ether II in the presence of Lewis acid to form a cationic complex, and treatment of the latter with allyl derivatives of boron or magnesium.

A Novel Method of Crossed-Aldol Condensation: Alkylation of Trimethylsilyl Enol Ethers by Alkyl 1-Chloro-2-arylthioalkyl Ethers

Trimethylsilyl enol ethers 5, derived from aldehydes or ketones, react with alkyl 1-chloro-2-arylthioalkyl ethers 3 (β-arylthio-α-chloroethers, prepared in situ from vinyl ethers 1 and arenesulfenyl chlorides 2) to give 2-alkoxy-3-arylthioalkyl ketone derivatives 6 in the presence of a Lewis acid.