96882-98-3 Usage
Uses
Used in Organic Synthesis:
(S)-(+)-2-(P-TOLUENESULFONATE)-1,2-PROPANEDIOL is used as a chiral resolving agent for the synthesis of enantiomerically pure compounds. Its optical purity ensures the production of single enantiomers, which is crucial for the development of pharmaceuticals with desired biological activities and reduced side effects.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (S)-(+)-2-(P-TOLUENESULFONATE)-1,2-PROPANEDIOL is used as a key intermediate in the synthesis of various drugs. Its chiral properties allow for the creation of enantiomerically pure active pharmaceutical ingredients, improving the efficacy and safety of medications.
Used in Asymmetric Synthesis Reactions:
(S)-(+)-2-(P-TOLUENESULFONATE)-1,2-PROPANEDIOL is used as a chiral auxiliary in asymmetric synthesis reactions to control the stereochemistry of the final product. This helps in obtaining enantiomerically enriched compounds, which are essential for the development of high-quality pharmaceuticals and other specialty chemicals.
Used in Research and Development:
In the field of research and development, (S)-(+)-2-(P-TOLUENESULFONATE)-1,2-PROPANEDIOL is utilized for studying the effects of chirality on chemical reactions and exploring new methods for enantioselective synthesis. Its unique properties make it a valuable tool for advancing the understanding of stereochemistry in organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 96882-98-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,6,8,8 and 2 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 96882-98:
(7*9)+(6*6)+(5*8)+(4*8)+(3*2)+(2*9)+(1*8)=203
203 % 10 = 3
So 96882-98-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H14O4S/c1-8-3-5-10(6-4-8)15(12,13)14-9(2)7-11/h3-6,9,11H,7H2,1-2H3/t9-/m0/s1
96882-98-3Relevant academic research and scientific papers
Enantioselective synthesis of (R)-propylene carbonate from ethyl (S)-lactate
Whitaker, John M.,Ronald, Robert C.
experimental part, p. 1403 - 1404 (2010/02/16)
We report a three-step synthesis of (R)-propylene carbonate from inexpensive, chiral ethyl (S)-lactate. The synthesis involves a borohydride ester reduction and an unusual intramolecular displacement reaction by a carbonate anion. The procedure is simple and reliable, resulting in (R)-propylene carbonate in approximately 60% overall yield with ≥98% ee. Georg Thieme Verlag Stuttgart.
SYNTHESIS OF THE ENANTIOMERS OF CIS-2-METHYL-5-HEXANOLIDE, THE MAJOR COMPONENT OF THE SEX PHEROMONE OF THE CARPENTER BEE
Mori, Kenji,Senda, Shuji
, p. 541 - 546 (2007/10/02)
(2R,5S)-2-Methyl-5-hexanolide and its antipode were synthesized in highly optically pure state (98-99percent e.e.) starting from ethyl (S)-lactate and the enantiomers of methyl β-hydroxyisobutyrate.The specific rotations of our samples were D +/- 91.0 -93.5 deg (CHCl3), while the reported values of the samples prepared by resolution or asymmetric synthesis were +/- 64.5-65.6 deg.
