96883-13-5

Upstream product

• 693-67-4 bromoundecane 
• 39637-99-5 (S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride 
• 96883-09-9 methyl (2S)-2-hydroxytridecanoate 
• 96947-51-2 (R)-2-chloroacetylaminotridecanoic acid 
• 96883-07-7 (+/-)-2-chloroacetylaminotridecanoic acid 
• 96883-08-8 (S)-2-hydroxytridecanoic acid 
• 405552-38-7 (R)-2-hydroxytridecanoic acid 
• 96947-50-1 (S)-2-aminotridecanoic acid 
• 5440-58-4 Acetamino-undecyl-malonsaeure-diaethylester 
• 35237-38-8 (+/-)-2-aminotridecenoic acid 
• 20445-33-4 (R)-methoxytrifluoromethylphenylacetyl chloride 
• 96883-10-2 methyl (R)-2-hydroxytridecanoate 

Relevant academic research and scientific papers

A novel one-pot procedure for the stereoselective synthesis of α-hydroxy esters from ortho esters

A novel one-pot procedure for the stereoselective synthesis of a-hydroxy esters from ortho esters was developed. Key steps were multiheteroatom Cope rearrangements of O-acylated N-hydroxy-L-tert-leucinol-derived oxazoline N-oxides leading to a-acyloxy oxazolines and, after methanolysis, to the target molecules in 67-80% yield and 94-98% ee.

SYNTHESIS OF THE ENANTIOMERS OF 5-HEXADECANOLIDE, THE PHEROMONE OF THE QUEEN OF THE ORIENTAL HORNET, VESPA ORIENTALIS, EMPLOYING ENZYMIC RESOLUTION OF (+/-)-2-AMINOTRIDECANOIC ACID AS THE KEY-STEP

Optical resolution of (+/-)-2-chloroacetylaminotridecanoic acid with amino acylase gave (S)-2-aminotridecanoic acid, which was converted into highly optically pure (S)-5-hexadecanolide (the pheromone of Vespa orientalis).Similarly (R)-2-chloroacetylaminot