96887-44-4

Upstream product

• 87-72-9 L-(+)-arabinose 
• 1233-03-0 1,2,3,4-tetra-O-acetyl-L-arabinopyranose 
• 943857-29-2 p-methoxyphenyl 2,3,4-tri-O-acetyl-α-L-arabinopyranoside 

Downstream Products

• 959793-40-9 p-methoxyphenyl 3,4-O-isopropylidene-α-L-arabinopyranoside 
• 1000413-27-3 p-methoxyphenyl 4-O-acetyl-α-L-arabinopyranoside 

Relevant academic research and scientific papers

Concise synthesis of two trisaccharides related to the saponin isolated from Centratherum anthelminticum

Chemical synthesis of two trisaccharides related to the saponin isolated from Centratherum anthelminticum is reported. Stereoselective, high-yielding glycosylation strategies were developed using H2SO4 immobilized on silica for activ

Organoboron-Promoted Regioselective Glycosylations in the Synthesis of a Saponin-Derived Pentasaccharide from Spergularia ramosa

Organoboron-mediated regioselective glycosylations were employed as key steps in the total synthesis of a branched pentasaccharide from a saponin natural product. The ability to use organoboron activation to differentiate OH groups in an unprotected glycosyl acceptor, followed by substrate-controlled reactions of the obtained disaccharide, enabled a streamlining of the synthesis relative to a protective group-based approach. This study revealed a matching/mismatching effect of the relative configuration of donor and acceptor on the efficiency of a regioselective glycosylation reaction, a problem that was solved through the development of a novel boronic acid-amine copromoter system for glycosyl acceptor activation.