96964-56-6

Basic information

• Product Name: 4-Benzenesulfonyl-2-ethyl-5-methoxy-3-oxo-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid methyl ester
• Synonyms: 4-Benzenesulfonyl-2-ethyl-5-methoxy-3-oxo-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid methyl ester
• CAS NO: 96964-56-6
• Molecular Weight: 402.468
• Mol File: 96964-56-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Benzenesulfonyl-2-ethyl-5-methoxy-3-oxo-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Benzenesulfonyl-2-ethyl-5-methoxy-3-oxo-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid methyl ester(96964-56-6)
• EPA Substance Registry System: 4-Benzenesulfonyl-2-ethyl-5-methoxy-3-oxo-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid methyl ester(96964-56-6)

Safety Data

• Hazardous Substances Data: 96964-56-6(Hazardous Substances Data)

Upstream product

• 88116-09-0 2-Benzenesulfonylmethyl-1-bromomethyl-3-methoxy-benzene 
• 26717-67-9 dimethyl ethylmalonate 

Relevant articles and documents

Annulation Reactions Leading to Naphtalene Derivatives. New Syntheses of Natural 1,2- and 1,4-Naphthoquinones

1-(Phenylsulfonyl)-2-oxo-3-(methoxycarbonyl)-1,2,3,4-tetrahydronaphthalene derivatives with various C-3 substituents were effectively prepared by a one-step cyclization involving 1--2-(bromomethyl)benzene derivatives and monosubstituted malonic esters.A high yield one-step decarboxylation-desulfonylation of the above products by lithium iodide led to C-3-substituted 2-naphthalenols 7a-g whereas prior C-1 alkylation of the cyclization products provided 1,3-dialkylated 2-naphthalenols 6s,b.Oxidations of compounds 7 to o-naphthoquinones 8a-f further oxidations of the above products to substituted 2-hydroxy-1,4-naphthoquinones provided a new pathway to naturally occuring naphthoquinones like phthiocol (9), droserone methyl ether (10), and lapachol (15).