96995-01-6Relevant academic research and scientific papers
Transformation of arctiin to estrogenic and antiestrogenic substances by human intestinal bacteria
Xie, Li-Hua,Ahn, Eun-Mi,Akao, Teruaki,Abdel-Hafez, Atef Abdel-Monem,Nakamura, Norio,Hattori, Masao
, p. 378 - 384 (2003)
After anaerobic incubation of arctiin (1) from the seeds of Arctium lappa with a human fecal suspension, six metabolites were formed, and their structures were identified as (-)-arctigenin (2), (2R,3R)-2-(3′,4′- dihydroxybenzyl)-3-(3″,4″-dimethoxybenzyl)b
Oxidative metabolism of the mammalian lignans enterolactone and enterodiol by rat, pig, and human liver microsomes
Jacobs, Eric,Metzler, Manfred
, p. 1071 - 1077 (2007/10/03)
Hepatic microsomes from aroclor-treated male Wistar rats biotransform enterolactone to 12 metabolites, six of which carry an additional hydroxy group at the aromatic and six at the aliphatic moiety according to HPLC/MS and GC/MS analysis. The aromatic hyd
Synthesis of the 2H>-Labelled Urinary Lignans Enterolactone and Enterodiol
Kirk, N. David,McLaughlin, Leo M.,Lawson, Alexander M.,Setchell, Kenneth D.R.,Patel, Shailesh K.
, p. 35 - 38 (2007/10/02)
Isotopically labelled forms of urinary lignans (+/-)-trans-2,3-bis-(3-hydroxybenzyl)butan-4-olide (enterolactone) and (+/-)2,3-bis-(3-hydroxybenzyl)butane-1,4-diol (enterodiol) have been synthesized from 2H2>butenolide, obtained from the furan-maleic anhydride adduct by reduction (NaBD4) and pyrolysis.
