97039-96-8Relevant academic research and scientific papers
THE CHEMISTRY OF THE PYRIDOCARBAZOLES PART 15. THE SYNTHESIS OF UNSYMMETRICALLY 1,4-DISUBSTITUTED CARBAZOLES AND THEIR USE IN THE SYNTHESIS OF 6H-PYRIDOCARBAZOLES
Hogan, Iain,Jenkins, Paul D.,Sainsbury, Malcolm
, p. 2943 - 2964 (2007/10/02)
A new construction of unsymmetrically 1,4-disubstituted carbazoles has been devised and used in the synthesis of the alkaloid olivacine.The starting materials are gramines and the sodium salts of 2-cyano-4-oxopentanonitriles.These afford 4-cyano-5-(indol-
AN EFFICIENT SYNTHESYS OF 3-ACYLCARBAZOLES AND OBSERVATIONS ON THE FURTHER ELABORATION OF THESE COMPOUNDS TO 6H-PYRIDOCARBAZOLES
Hogan, Iain,Jenkins, Paul,Sainsbury, Malcolm
, p. 6505 - 6508 (2007/10/02)
A new procedure for the synthesis of 3-acylcarbazoles useful for the construction of 6H-pyridocarbazoles is described starting from readily available gramines or indoles.This methodology is exemplified by a synthesis of the anticancer alkaloid olivacine.Some discrepancies are noted between our results and those of other authors.
