97065-56-0

Basic information

• Product Name: Benzene, 1-(2,2-dibromoethenyl)-3-methyl-
• Synonyms: Benzene,1-(2,2-dibromoethenyl)-3-methyl
• CAS NO: 97065-56-0
• Molecular Formula: C9H8Br2
• Molecular Weight: 275.971
• Mol File: 97065-56-0.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(2,2-dibromoethenyl)-3-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(2,2-dibromoethenyl)-3-methyl-(97065-56-0)
• EPA Substance Registry System: Benzene, 1-(2,2-dibromoethenyl)-3-methyl-(97065-56-0)

Safety Data

• Hazardous Substances Data: 97065-56-0(Hazardous Substances Data)

Upstream product

• 81559-59-3 1-Methyl-3-(2,2,2-tribromo-ethyl)-benzene 
• 620-13-3 1-bromomethyl-3-methyl-benzene 
• 558-13-4 carbon tetrabromide 
• 620-23-5 m-tolyl aldehyde 

Downstream Products

• 115665-69-5 (Z)-1-(2-bromovinyl)-3-methylbenzene 
• 804549-56-2 1,3-benzothiazol-2-yl(3-methylphenyl)methanone 
• 33675-43-3 1-(bromo-ethynyl)-3-methyl-benzene 
• 1589517-56-5 (Z)-1-(2-bromo-2-phenylvinyl)-3-methylbenzene 
• 14064-48-3 (E)-3-methylstilbene 
• 1315481-71-0 diethyl P-[2-(3-methylphenyl)ethynyl]phosphonate 
• 1616878-00-2 3-(m-tolylethynyl)indolizine-1-carbonitrile 
• 827574-77-6 1-[2-(4-methoxyphenyl)ethynyl]-3-methylbenzene 
• 29835-27-6 3-(3-methylphenyl)prop-2-ynoic acid 
• 14674-99-8 1-phenyl-3-(3-methylphenyl)prop-2-yn-1-one 
• 14635-91-7 1-methyl-3-(2-phenylethynyl)benzene 
• 58686-70-7 ethyl 3-(m-tolyl)propiolate 
• 1301683-20-4 ethyl 2-methyl-5-(3-methylphenyl)furan-3-carboxylate 
• 62358-91-2 3-(3-methylphenyl)prop-2-ynal 

Relevant articles and documents

Synthesis of Chiral Propargylamines, Chiral 1,2-Dihydronaphtho[2,1-b]furans and Naphtho[2,1-b]furans with C-Alkynyl N,N′-di-(tert-butoxycarbonyl)-aminals and β-Naphthols

Chiral phosphoric acid-catalyzed couplings of C-alkynyl N,N′-di-(tert-butoxycarbonyl)-aminals with β-naphthols led to chiral propargylamines in moderate to high yields with high to excellent enantioselectivity, in which the reactions underwent sequential chiral phosphoric acid-catalyzed in situ formation of N-(tert-butoxycarbonyl)-imines (N-Boc-imines) from the aminals, and 1,2-addition of β-naphthols to the N-Boc-imines. Chiral 1,2-dihydronaphtho[2,1-b]furans and naphtho[2,1-b]furans were prepared with satisfactory results when 10 mol% AgOAc and 20 mol% 2,6-lutidine or 1.2 equiv. of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) were added to the resulting chiral propargylamines solution, respectively.

Pd-Catalyzed Indole Synthesis via C-H Activation and Bisamination Sequence with Diaziridinone

This work describes an efficient Pd-catalyzed indole synthesis. A wide variety of indoles can be obtained in good yields from readily available vinyl bromides. The reaction likely proceeds through a sequential aryl C-H activation and bisamination of a resulting pallada(II)cycle with diaziridinone.

Synthesis of Chiral β-Borylated Carboxylic Esters via Nickel-Catalyzed Asymmetric Hydrogenation

The highly efficient Ni-catalyzed asymmetric hydrogenation of β-boronic ester substituted-α,β-unsaturated carboxylic esters was successfully developed using (S,S)-Ph-BPE as the ligand. A series of chiral β-borylated carboxylic esters were obtained with high yields (94%-99% yields) and excellent enantioselectivities (89%-99% ee). The gram-scale asymmetric hydrogenation with a low catalyst loading (0.25 mol %) and synthetic transformation of hydrogenation product demonstrated the great synthetic utility of this methodology.