97099-94-0

Basic information

• Product Name: 6-Methylene-3-phenyl-6,7-dihydro-thiazolo[2,3-c][1,2,4]triazin-4-one
• CAS NO: 97099-94-0
• Molecular Weight: 243.289
• Mol File: 97099-94-0.mol

Chemical Properties

• CAS DataBase Reference: 6-Methylene-3-phenyl-6,7-dihydro-thiazolo[2,3-c][1,2,4]triazin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Methylene-3-phenyl-6,7-dihydro-thiazolo[2,3-c][1,2,4]triazin-4-one(97099-94-0)
• EPA Substance Registry System: 6-Methylene-3-phenyl-6,7-dihydro-thiazolo[2,3-c][1,2,4]triazin-4-one(97099-94-0)

Safety Data

• Hazardous Substances Data: 97099-94-0(Hazardous Substances Data)

Upstream product

• 97099-91-7 3-(1-Methyl-prop-2-ynylsulfanyl)-6-phenyl-2H-[1,2,4]triazin-5-one 
• 447-00-7 6-phenyl-1,2,4-triazine-3(2H)-thione-5(4H)-one 
• 97099-89-3 6-Phenyl-3-prop-2-ynylsulfanyl-2H-[1,2,4]triazin-5-one 

Relevant articles and documents

PALLADIUM-CATALYZED CYCLIZATION REACTIONS. UNICQUE SYNTHESIS OF CONDENSED THIAZOLES

The facile synthesis of 3-methylene-2,3-dihydro-5H-thiazolopyrimidin-5-ones (9) has been performed by the catalytic action of a Pd(II) salt on 4-propargylthiopyrimidin-2(1H)-ones (6).Similar Pd(II)-catalyzed cyclization of 3-propargylthio-1,2,4-triazin-5(2H)-ones (10) gives 6-methylene-6,7-dihydro-4H-thiazolotriazin-4-ones (11) as a main product. 3-methylene-2,3-dihydro-7H-thiazolotriazin-7-ones (12), the regioisomers of 11, are provided by a base-catalyzed cyclization of 10.

PALLADIUM-CATALYZED CYCLIZATION REACTIONS OF 3-PROPARGYLTHIO-1,2,4-TRIAZIN-5(2H)-ONES TO THIAZOLO-1,2,4-TRIAZINONES

Selective transformation of 3-propargylthio-1,2,4-triazin-5(2H)-ones (1) to 6-methylene-6,7-dihydro-4H-thiazolo- triazin-4-ones (2) and 3-methylene-2,3-dihydro-7H-thiazolotriazin-7-ones (3) is performed under the conditions of Pd(II) salt or sodium hydroxide catalysis, respectively.