97109-46-1

Usage

Uses

Used in Medicinal Chemistry:
1,3,4-Thiadiazole, 2-bromo-5-(methylthio)is used as a building block in the synthesis of various pharmaceutical compounds due to its unique structure and properties. It serves as a starting material for the development of new drugs, contributing to the creation of diverse functionalized thiadiazole derivatives with potential biological activities.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1,3,4-Thiadiazole, 2-bromo-5-(methylthio)is utilized as a key intermediate for the synthesis of compounds with therapeutic potential. Its presence in the molecular structure of these compounds can influence their pharmacological properties, making it an essential component in drug discovery and development processes.

Upstream product

• 5319-77-7 2-amino-5-methylthio-1,3,4-thiadiazole 

Relevant academic research and scientific papers

AZOLE COMPOUNDS AS PIM INHIBITORS

The invention relates to bicyclic compounds of formulas I and Ia, and salts thereof. In some embodiments, the invention relates to inhibitors or modulators of Pim-1 and/or Pim-2, and/or Pim-3 protein kinase activity or enzyme function. In still further em

AZOLYL PIPERAZINYL PHENYL OXAZOLIDINONE ANTIMICROBIALS

Compounds useful in the preparation of pharmaceutical preparations for the treatment of microbial infection where such compounds are of structural Formula I I or pharmaceutically acceptable salts thereof wherein: R1 is -CHO, -COCH3, -COCHCl2, -COCHF2, -CO2CH3, -SO2CH3, or -COCH2OH; X1 and X2 are independently H, F, or Cl; and Q is a five membered ting heterocycle (azolyl ring) of the general form: wherein A, B, and C are independently oxygen (O), nitrogen (N), sulfur (S) or Carbon (C). In all cases, the piperazine nitrogen atom is attached at the carbon atom of the carbon-nitrogen double bond.

Azolyl piperazinyl phenyl oxazolidinone antimicrobials

Compounds useful in the preparation of pharmaceutical preparations for the treatment of microbial infection where such compounds are of structural Formula I STR1 or pharmaceutically acceptable salts thereof wherein: R1 is --CHO, --COCH3, --COCHCl2, --COCHF2, --CO2 CH3, --SO2 CH3, or --COCH2 OH; X1 and X2 are independently H, F, or Cl; and Q is a five membered ting heterocycle (azolyl ring) of the general form: STR2 wherein A, B, and C are independently oxygen (O), nitrogen (N), sulfur (S) or Carbon (C). In all cases, the piperazine nitrogen atom is attached at the carbon atom of the carbon-nitrogen double bond.