97132-10-0Relevant academic research and scientific papers
Access to the new isoindolo[1,3]benzothiazocinones via the combination of N-acyliminium chemistry and friedel-crafts type π-cyclization
Cul, Armelle,Daich, Adam,Decroix, Bernard,Sanz, Gerard,Van Hijfte, Luc
, p. 33 - 39 (2007/10/03)
New racemic and chiral [4,2]- and [3,5]benzothiazocines (4) and (5) in the isoindolinone series were synthesized easily in few steps based on the combination of N-acyliminium chemistry and π-cationic cyclization of acylium ions. The chemoselectivity observed during these processes, particularly in the reduction, the thioalkylation and the cyclization stages, were also discussed.
Introduction of a carboxymethylamino (or oxy or thio) group in the 3 position of 2-aryl (or arylmethyl) isoindol-1-ones from α hydroxylactams
Pigeon, Pascal,Decroix, Bernard
, p. 1423 - 1431 (2007/10/03)
The preparation of 3-carboxymethylamino (or oxy or thio)-2-aryl (or arylmethyl)-isoindol-1 ones are described from hydroxylactams according to three different pathways.
Note on the Synthesis of 3-isoindolinones from Methyl 2- Formylbenzoate
Liebl, Rainer,Handte, Reinhard
, p. 1093 - 1094 (2007/10/02)
In a one-pot procedure the isoindolinone derivatives 6 have been obtained from methyl 2-formylbenzoate, primary amines, and thiols via the intermediate imines 1.
