97138-17-5Relevant academic research and scientific papers
Ru-catalyzed asymmetric hydrogenation of γ-heteroatom substituted β-keto esters
Fan, Weizheng,Li, Wanfang,Ma, Xin,Tao, Xiaoming,Li, Xiaoming,Yao, Ying,Xie, Xiaomin,Zhang, Zhaoguo
experimental part, p. 9444 - 9451 (2012/01/13)
A series of enantiomerically pure γ-heteroatom substituted β-hydroxy esters were synthesized with high enantioselectivities (up to 99.1% ee) by hydrogenation of γ-heteroatom substituted β-keto esters in the presence of Ru-(S)-SunPhos catalyst. These asymmetric hydrogenations provide key building blocks for a variety of naturally occurring and biologically active compounds.
PREPARATION OF α-DIAZO-β-KETOSULFONES BY DIAZO-TRANSFER REACTION WITH AN IN SITU GENERATED AZIDINIUM SALT. A SAFE AND EFFICIENT PROCEDURE FOR THE DIAZO-TRANSFER REACTION IN NEUTRAL MEDIUM.
Monteiro, H. J.
, p. 983 - 992 (2007/10/02)
An efficinet and mild procedure is described for the preparation of α-diazo-β-ketosulfones using an azidinium salt generated in situ from relatively inexpensive and safe chemicals.The method is equally applicable to other CH2-acidic compounds.
