97141-36-1Relevant academic research and scientific papers
Simple syntheses of N-alkylated spermidine fragments and analogues of the spermine alkaloid kukoamine A
Vassis, Stratos,Karigiannis, George,Balayiannis, George,Militsopoulou, Maria,Mamos, Petros,Francis, George W.,Papaioannou, Dionissios
, p. 1579 - 1582 (2007/10/03)
Acylation of a variety of amines with succinimidyl N-trityl-β-alanyl-γ-aminobutyrate and N-trityl-γ-aminobutyryl-β-alaninate, readily obtained through coupling of succinimidyl N-trityl-β-alaninate with trimethylsilyl γ-aminobutyrate and of N-trityl-γ-aminobutyric acid with methyl β-alaninate, respectively, followed by LiAlH4 reduction, produced N-monoalkylated spermidine fragments and analogues of the spermine alkaloid kukoamine A. The applicability of this methodology on the solid phase was also demonstrated.
