97142-97-7

Upstream product

• 88356-92-7 1-[4-(methylthio)phenyl]-2-propanone 
• 97142-98-8 4-dimethylamino-3-(4-methylthiophenyl)-3-buten-2-one 
• 107-91-5 cyanoacetic acid amide 

Downstream Products

• 144296-73-1 6-methyl-5-(4-methylsulphonylphenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide 
• 144296-78-6 6-methyl-5-(4-methylsulphonylphenyl)-2-oxo-3-amino-1,2-dihydropyridine 
• 144296-72-0 6-methyl-5-(4-methylsulphenylphenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide 
• 144296-77-5 6-methyl-5-(4-methylsulphenylphenyl)-2-oxo-3-amino-1,2-dihydropyridine 
• 97143-03-8 6-methyl-5-(4-methylsulphonylphenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile 
• 97143-01-6 6-methyl-5-(4-methylsulphenylphenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile 
• 144296-71-9 6-methyl-5-(4-methylthiophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide 

Relevant academic research and scientific papers

New cardiotonic agents related to amrinone: Synthesis of 1,2-dihydro-5-arylpyridin-2-ones

For development of new cardiotonic agents a serie of 5-aryl-3,4-dihydropyridin-2(1H)-ones, related to amrinone have been prepared from methylquinolines, 2-arylacetic acid or 3-arylethanones by direct aminomethylenation and subsequent condensation-cyclizat

6-Alkyl-5-[4-(alkylsulfinyl or alkylsulfonyl)phenyl]-2(1H)-pyridinones and their use as cardiatonics

3-Q-5-[4-(R'-X)phenyl]-6-R-2(1H)-pyridinones (I), where R and R' are each methyl or ethyl, X is sulfinyl when Q is hydrogen or cyano, or X is sulfonyl when Q is cyano, their preparation and cardiotonic use are shown. Also shown are intermediates 5-[4-(R'-