97164-96-0 Usage
Uses
Used in Pharmaceutical Industry:
1H-Azepine-4-carboxylic acid, hexahydro-(9CI) is used as a key intermediate in the synthesis of various pharmaceuticals for its hexahydroazepine core structure, which is found in many bioactive compounds. This makes it instrumental in the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 1H-Azepine-4-carboxylic acid, hexahydro-(9CI) is utilized as a precursor in the production of agrochemicals, contributing to the development of effective pesticides and other agricultural chemicals that enhance crop protection and yield.
Used in Research and Development:
1H-Azepine-4-carboxylic acid, hexahydro-(9CI) is employed as a building block in research and development for the synthesis of new compounds with potential biological activity. Its unique structure allows scientists to explore its properties and applications in creating innovative molecules for various scientific and medical purposes.
Check Digit Verification of cas no
The CAS Registry Mumber 97164-96-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,7,1,6 and 4 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 97164-96:
(7*9)+(6*7)+(5*1)+(4*6)+(3*4)+(2*9)+(1*6)=170
170 % 10 = 0
So 97164-96-0 is a valid CAS Registry Number.
97164-96-0Relevant academic research and scientific papers
GABA agonists. Synthesis and structure-activity studies on analogues of isoguvacine and THIP
Krogsgaard-Larsen,Roldskov-Christiansen
, p. 157 - 164 (2007/10/04)
A series of analogues of the specific GABA receptor agonists isoguvacine, isonipecotic acid, and THIP (4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol) have been synthesized and tested as inhibitors of the binding of 3H-GABA to GABA receptor sites on rat brain membranes in vitro. Introduction of a hydroxy group into the 3- or 4-position of isonipecotic acid results in compounds with considerably reduced receptor affinity. The 7-membered ring analogues of isoguvacine and isonipecotic acid are more than two orders of magnitude weaker than the parent compounds. Replacement of the 3-isoxazolol unit of THIP by related heterocyclic rings also result in dramatic loss of activity. Thus iso-THIP (4,5,6,7-tetrahydroisoxazolo[3,4-c]pyridin-3-ol) is a weak inhibitor of 3H-GABA binding, whereas the 3-pyrazolol THIP analogues are inactive.
