97217-82-8 Usage
Description
(±)-BAY-k-8644 is a synthetic dihydropyridine derivative that functions as a potent and selective calcium channel opener. It is renowned for its ability to enhance the influx of calcium ions into cells by promoting the opening of L-type calcium channels, thereby increasing intracellular calcium levels. This unique mechanism of action makes (±)-BAY-k-8644 a valuable asset in the field of calcium channel research and drug development.
Uses
Used in Pharmaceutical Research:
(±)-BAY-k-8644 is used as a research tool for studying the effects of calcium channel activation on various biological processes. Its ability to selectively activate L-type calcium channels makes it particularly useful in understanding the role of calcium ions in smooth muscle contraction, neurotransmitter release, and neuronal excitability.
Used in Drug Development:
(±)-BAY-k-8644 serves as a lead compound in the development of new drugs targeting calcium channels. Its potent and selective activity allows researchers to explore its potential therapeutic applications in treating conditions related to calcium channel dysfunction, such as cardiovascular diseases, neurological disorders, and muscle disorders.
Used in Smooth Muscle Contraction Studies:
(±)-BAY-k-8644 is used as an experimental agent to investigate the role of calcium channels in smooth muscle contraction. By modulating intracellular calcium levels, researchers can gain insights into the mechanisms underlying smooth muscle function and develop targeted therapies for related conditions.
Used in Neurotransmitter Release Research:
(±)-BAY-k-8644 is utilized as a research compound to study the impact of calcium channel activation on neurotransmitter release. This helps in understanding the intricate relationship between calcium ions and neuronal signaling, which is crucial for the development of treatments for neurological disorders.
Used in Neuronal Excitability Studies:
(±)-BAY-k-8644 is employed as a research tool to explore the effects of calcium channel activation on neuronal excitability. This knowledge is vital for advancing our understanding of neuronal function and developing treatments for conditions that involve altered neuronal excitability.
Check Digit Verification of cas no
The CAS Registry Mumber 97217-82-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,7,2,1 and 7 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 97217-82:
(7*9)+(6*7)+(5*2)+(4*1)+(3*7)+(2*8)+(1*2)=158
158 % 10 = 8
So 97217-82-8 is a valid CAS Registry Number.
97217-82-8Relevant articles and documents
Method of combatting coronary and vascular diseases
-
, (2008/06/13)
1,4-Dihydropyridines of the formula STR1 in which n is 0,1 or 2, and R1 to R7 can have a wide variety of meanings, which possess inotropic action, and many of which are new, are useful in increasing the influx of Ca++ into
