97218-67-2

Upstream product

• 59378-98-2 5-tert-butyl methyl glutarate 
• 1519-39-7 (R)-methyl p-tolyl sulfoxide 
• 112572-16-4 lithium (R_S)-(+)-methyl p-tolyl sulfoxide 
• 97218-64-9 (R) t-butyl-5-oxo-6-p-tolylsulfinyl hexanoate 

Relevant academic research and scientific papers

Asymmetric Synthesis of the C-1-C-8 Fragment of Leukotriene B4 and C-11-C-20 Fragments of Leukotriene B4 and 12(S)-Hydroxy-5,8,14(Z), 10(E) Eicosatetraenoic Acid

An asymmetric synthesis of the C-1-C-8 fragment of LTB4 based on the reduction of optically active β-ketosulfoxides is described as well as the asymmetric synthesis of the C-11-C-20 fragments of LTB4 and 12(S)-hydroxy-5,8,14(Z), 10(E

Highly Diastereoselective Reduction of Chiral β-Ketosulphoxides under Chelation Control: Application to the Synthesis of (R)-(+)-n-Hexadecano-1,5-lactone

The presence of zinc chloride in the reduction of chiral β-ketosulphoxides with di-isobutylaluminium hydride effects high 1,3-asymmetric induction to give β-hydroxysulphoxides; this method can be successfully applied to the synthesis of optically pure 1,4