97313-83-2Relevant academic research and scientific papers
Radioprotective agents having an amino-thioalkyl structure
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, (2008/06/13)
A pharmaceutical composition effective in the protection of normal tissues against radiation induced damage comprising administration a compound of the formula in which R1 is a radical corresponding to an amino acid R1 --COOH, /A/ is a C2 or C3 alkylene radical which can be substituted with a C1 to C3 alkyl radical, or with a hydroxy or hydroxycarbonyl radical or a --COR radical where R is an amino or --NH--CH2 --CO2 H radical, R2 is an acyl radical which protects the thiol group and which liberates the thiol group in vivo, R3 is a hydrogen, and also the salts of this compound with pharmaceutically acceptable acids.
