97314-41-5

Upstream product

• 106-47-8 4-chloro-aniline 
• 96960-72-4 5-Acetylamino-1H-imidazole-4-carboxamide hydrochloride 

Downstream Products

• 104091-36-3 (2R,4R,5S)-4-[6-(4-Chloro-phenylamino)-2-methyl-purin-9-yl]-tetrahydro-pyran-2,5-diol 
• 104091-26-1 (2S,4R,5S)-4-[6-(4-Chloro-phenylamino)-2-methyl-purin-9-yl]-tetrahydro-pyran-2,5-diol 
• 115043-43-1 (2R,3R,4S,5R)-2-[6-(4-Chloro-phenylamino)-2-methyl-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol 

Relevant academic research and scientific papers

Method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK)

The present invention relates to a method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK) and the use of the compounds in the prevention or treatment of disease, including pre-diabetes, type 2 diabetes, syndrome X, metabolic syndrome and obesity.

Phosphorus Pentoxide in Organic Synthesis, XVI. - A One-step Synthesis of 2-Methyl-N6-aryladenines from 5-Acetylamino-1H-imidazole-4-carboxamide Hydrochloride

5-Amino-1H-imidazole-4-carboxamide hydrochloride has been converted into a series of 2-methyl-6-(arylamino)purines 3 via 5-acetylamino-1H-imidazole-4-carboxamide hydrochloride (1) which was heated with phosphorus pentoxide, triethylamine hydrochloride, and an appropriate substituted aniline at 180 deg C.