97315-77-0

Basic information

• Product Name: L-Glutamic acid, 3-fluoro-, threo- (9CI)
• Synonyms: L-Glutamic acid, 3-fluoro-, threo- (9CI)
• CAS NO: 97315-77-0
• Molecular Formula: C5H8FNO4
• Molecular Weight: 165.1197232
• Product Categories: GLYCINESCAFFOLD
• Mol File: 97315-77-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: L-Glutamic acid, 3-fluoro-, threo- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: L-Glutamic acid, 3-fluoro-, threo- (9CI)(97315-77-0)
• EPA Substance Registry System: L-Glutamic acid, 3-fluoro-, threo- (9CI)(97315-77-0)

Safety Data

• Hazardous Substances Data: 97315-77-0(Hazardous Substances Data)

Upstream product

• 1608-58-8 diethyl 2-oxo-3-carbetoxy-3-fluoroglutarate 
• 19883-18-2 D,L-threo-N-acetyl-3-fluoroglutamic acid 
• 117860-25-0 disodium 2-oxo-3-fluoroglutarate 
• 97315-80-5 N-acetyl-3-hydroxyglutamic acid 

Downstream Products

• 97315-82-7 methyl cis-3-fluoro-5-ketopyrrolidine-2-carboxylate 

Relevant articles and documents

L-threo- and L-erythro-3-Fluoroglutamic Acids. Synthesis by Fluorodehydroxylation and Enzymatic Resolution.

threo- and erythro-3-fluoroglutamic acids were prepared by fluorodehydroxylation of N-acetyl-3-hydroxyglutamic acids according to Kollonitsch.Following ion exchange column separation of the diastereoisomers, enzymatic deacylation by acylase I afforded optically pure L-isomers of the 3-fluoroglutamic acid.Assignment of structure was achieved by correlation with cis- and trans-3-fluoropyroglutamic acids.The results indicate predominant inversion of configuration during the fluorodehydroxylation reaction.